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BDBM50017523 7-Fluoro-2-methyl-10-(4-methyl-piperazin-1-yl)-2,4-dihydro-1,2,3,4,9-pentaaza-benzo[f]azulene::CHEMBL308071

SMILES: CN1CCN(CC1)C1=Nc2cc(F)ccc2Nc2nn(C)nc12

InChI Key: InChIKey=PHMRBSUBYLCOFX-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50017523   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Muscarinic acetylcholine receptor


(RAT)
BDBM50017523
PNG
(7-Fluoro-2-methyl-10-(4-methyl-piperazin-1-yl)-2,4...)
Show SMILES CN1CCN(CC1)C1=Nc2cc(F)ccc2Nc2nn(C)nc12
Show InChI InChI=1S/C15H18FN7/c1-21-5-7-23(8-6-21)15-13-14(20-22(2)19-13)17-11-4-3-10(16)9-12(11)18-15/h3-4,9H,5-8H2,1-2H3,(H,17,20)
PDB

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/a>1.00E+3n/an/an/an/an/an/a



Lilly Research Centre Limited

Curated by ChEMBL


Assay Description
Inhibitory activity against Muscarinic acetylcholine receptor in male olac rat brain, using [3H]-QNB as the radioligand


J Med Chem 32: 2375-81 (1989)


Article DOI: 10.1021/jm00130a025
BindingDB Entry DOI: 10.7270/Q2FN16RX
More data for this
Ligand-Target Pair
DRD2


(BOVINE)
BDBM50017523
PNG
(7-Fluoro-2-methyl-10-(4-methyl-piperazin-1-yl)-2,4...)
Show SMILES CN1CCN(CC1)C1=Nc2cc(F)ccc2Nc2nn(C)nc12
Show InChI InChI=1S/C15H18FN7/c1-21-5-7-23(8-6-21)15-13-14(20-22(2)19-13)17-11-4-3-10(16)9-12(11)18-15/h3-4,9H,5-8H2,1-2H3,(H,17,20)
UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/a 840n/an/an/an/an/an/a



Lilly Research Centre Limited

Curated by ChEMBL


Assay Description
Inhibitory activity against Dopamine receptor D2 in calf caudate tissue, using [3H]spiperone as the radioligand


J Med Chem 32: 2375-81 (1989)


Article DOI: 10.1021/jm00130a025
BindingDB Entry DOI: 10.7270/Q2FN16RX
More data for this
Ligand-Target Pair