BDBM50017691 CHEMBL126075::dilazep

SMILES COc1cc(cc(c1OC)OC)C(=O)OCCCN2CCCN(CC2)CCCOC(=O)c3cc(c(c(c3)OC)OC)OC

InChI Key InChIKey=QVZCXCJXTMIDME-UHFFFAOYSA-N

Data  5 IC50

PDB links: 1 PDB ID matches this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50017691   

LigandChemical structure of BindingDB Monomer ID 50017691BDBM50017691(CHEMBL126075 | dilazep)
Affinity DataIC50: 600nMAssay Description:Inhibition of binding of Batrachotoxinin [3H]BTX-B to high affinity sites on voltage dependent sodium channels in a vesicular preparation from guinea...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2018
Entry Details Article
PubMed
TargetATP-binding cassette sub-family C member 4(Human)
The Netherlands Cancer Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50017691BDBM50017691(CHEMBL126075 | dilazep)
Affinity DataIC50: 2.00E+4nMAssay Description:TP_TRANSPORTER: inhibition of 9-(2-phosphonomethoxyethyl)adenine(PMEA) efflux (PMEA: 1 uM) in MRP4-expressing HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetATP-binding cassette sub-family C member 5(Human)
The Netherlands Cancer Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50017691BDBM50017691(CHEMBL126075 | dilazep)
Affinity DataIC50: 5.00E+4nMAssay Description:TP_TRANSPORTER: inhibition of 9-(2-phosphonomethoxyethyl)adenine(PMEA) efflux (PMEA: 1 uM) in MRP5-expressing HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed