BDBM50018229 2-(4-Hydroxy-phenyl)-2-phenyl-propionic acid 2-diethylamino-ethyl ester::CHEMBL37372

SMILES CCN(CC)CCOC(=O)C(C)(c1ccccc1)c1ccc(O)cc1

InChI Key InChIKey=WFXACEPWPCLBGC-UHFFFAOYSA-N

Data  7 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50018229   

TargetMuscarinic acetylcholine receptor M2(Homo sapiens (Human))
Walter Reed Army Institute Of Research

Curated by ChEMBL
LigandPNGBDBM50018229(2-(4-Hydroxy-phenyl)-2-phenyl-propionic acid 2-die...)
Affinity DataKi:  0.165nMAssay Description:Displacement of [3H] N-methylscopolamine from human muscarinic M2 receptor expressed in CHOK1 cells after 30 mins by scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M1(Homo sapiens (Human))
Walter Reed Army Institute Of Research

Curated by ChEMBL
LigandPNGBDBM50018229(2-(4-Hydroxy-phenyl)-2-phenyl-propionic acid 2-die...)
Affinity DataKi:  0.881nMAssay Description:Displacement of [3H] N-methylscopolamine from human muscarinic M1 receptor expressed in CHOK1 cells after 30 mins by scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M2(RAT)
Institute Of Research

Curated by ChEMBL
LigandPNGBDBM50018229(2-(4-Hydroxy-phenyl)-2-phenyl-propionic acid 2-die...)
Affinity DataKi:  5.60nMAssay Description:Inhibition of carbachol-induced release of alpha-amylase from pancreatic acinar cells from that of rat ileum contained the M2 receptor subtypesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M1(Homo sapiens (Human))
Walter Reed Army Institute Of Research

Curated by ChEMBL
LigandPNGBDBM50018229(2-(4-Hydroxy-phenyl)-2-phenyl-propionic acid 2-die...)
Affinity DataKi:  44nMAssay Description:Displacement of [3H] N-methylscopolamine from human muscarinic M1 receptor after 30 mins by scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M3(Homo sapiens (Human))
Walter Reed Army Institute Of Research

Curated by ChEMBL
LigandPNGBDBM50018229(2-(4-Hydroxy-phenyl)-2-phenyl-propionic acid 2-die...)
Affinity DataKi:  52.2nMAssay Description:Displacement of [3H] N-methylscopolamine from human muscarinic M3 receptor expressed in CHOK1 cells after 30 mins by scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic receptor M1(Bos taurus)
Institute Of Research

Curated by ChEMBL
LigandPNGBDBM50018229(2-(4-Hydroxy-phenyl)-2-phenyl-propionic acid 2-die...)
Affinity DataKi:  100nMAssay Description:Inhibition of [3H]NMS binding to cerebral cortex membranes which contain predominantly the Muscarinic acetylcholine receptor M1 subtypesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M4(Homo sapiens (Human))
Walter Reed Army Institute Of Research

Curated by ChEMBL
LigandPNGBDBM50018229(2-(4-Hydroxy-phenyl)-2-phenyl-propionic acid 2-die...)
Affinity DataKi:  566nMAssay Description:Displacement of [3H] N-methylscopolamine from human muscarinic M4 receptor expressed in CHOK1 cells after 30 mins by scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed