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BDBM50018394 5,5-Bis-(3,4-dimethoxy-phenyl)-penta-2,4-dienoic acid (1-methyl-4-pyridin-3-yl-butyl)-amide::CHEMBL53372

SMILES: [#6]-[#8]-c1ccc(cc1-[#8]-[#6])-[#6](=[#6]/[#6]=[#6]/[#6](=O)-[#7]-[#6@H](-[#6])-[#6]-[#6]-[#6]-c1cccnc1)\c1ccc(-[#8]-[#6])c(-[#8]-[#6])c1

InChI Key: InChIKey=KYAGZPGUYGDWKP-ZCQBWMKESA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50018394   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Platelet activating factor receptor


(Homo sapiens (Human))
BDBM50018394
PNG
(5,5-Bis-(3,4-dimethoxy-phenyl)-penta-2,4-dienoic a...)
Show SMILES COc1ccc(cc1OC)C(=C\C=C\C(=O)N[C@H](C)CCCc1cccnc1)c1ccc(OC)c(OC)c1
Show InChI InChI=1S/C31H36N2O5/c1-22(9-6-10-23-11-8-18-32-21-23)33-31(34)13-7-12-26(24-14-16-27(35-2)29(19-24)37-4)25-15-17-28(36-3)30(20-25)38-5/h7-8,11-22H,6,9-10H2,1-5H3,(H,33,34)/b13-7+/t22-/m1/s1
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Similars

Article
PubMed
n/an/a 50n/an/an/an/an/an/a



Roche Research Center

Curated by ChEMBL


Assay Description
Inhibition of platelet activating factor receptor binding activity in dog platelets using [3H]-PAF as radioligand


J Med Chem 32: 1820-35 (1989)


Article DOI: 10.1021/jm00128a026
BindingDB Entry DOI: 10.7270/Q2NZ86MR
More data for this
Ligand-Target Pair