BDBM50018427 1,3-Dimethyl-8-phenyl-2-thioxo-1,2,3,7-tetrahydro-purin-6-one::CHEMBL292157

SMILES Cn1c2nc([nH]c2c(=O)n(C)c1=S)-c1ccccc1

InChI Key InChIKey=IKXZVASJNSIQGY-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50018427   

TargetAdenosine receptor A1(Rat)
Niddk

Curated by ChEMBL
LigandPNGBDBM50018427(CHEMBL292157 | 1,3-Dimethyl-8-phenyl-2-thioxo-1,2,...)
Affinity DataKi:  38nMAssay Description:Inhibition of 1 nM [3H]N-6-(phenylisopropyl)adenosine binding to A1 receptors in rat cortical membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/19/2012
Entry Details Article
PubMed
TargetAdenosine receptor A2a/A2b(Rat)
Niddk

Curated by ChEMBL
LigandPNGBDBM50018427(CHEMBL292157 | 1,3-Dimethyl-8-phenyl-2-thioxo-1,2,...)
Affinity DataKi: >7.00E+3nMAssay Description:Inhibition of binding of [3H]5'-(N-ethylcarbamoyl)-adenosine to adenosine A2 receptor in rat striatal membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/19/2012
Entry Details Article
PubMed