BDBM50018478 5-(3-Ethoxy-4,5-dimethoxy-benzyl)-pyrimidine-2,4-diamine::CHEMBL23609::TCMDC-137664

SMILES CCOc1cc(Cc2cnc(N)nc2N)cc(OC)c1OC

InChI Key InChIKey=MJBWRUCEYONERX-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50018478   

TargetDihydrofolate reductase(Escherichia coli)
Wellcome Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50018478(5-(3-Ethoxy-4,5-dimethoxy-benzyl)-pyrimidine-2,4-d...)
Affinity DataKi:  0.5nMAssay Description:In vitro inhibition of rat liver dihydrofolate reductase.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Staphylococcus aureus)
Wellcome Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50018478(5-(3-Ethoxy-4,5-dimethoxy-benzyl)-pyrimidine-2,4-d...)
Affinity DataKi:  2.5nMAssay Description:Antibacterial activity against Staphylococcus aureusMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed