BDBM50018769 CHEMBL3291346
SMILES [H][C@@]12CC[C@@](C)(c3c1c(=O)n(-c1ccc(F)cc1F)n3Cc1ccccc1)C2(C)C
InChI Key InChIKey=PHUJLIRGKVQXJQ-OSPHWJPCSA-N
Data 3 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 50018769
Affinity DataIC50: 6.10E+3nMAssay Description:Inhibition of CYP3A4 (unknown origin)More data for this Ligand-Target Pair
Target11-beta-hydroxysteroid dehydrogenase 1(Rattus norvegicus (rat))
Hoffmann-La Roche
Curated by ChEMBL
Hoffmann-La Roche
Curated by ChEMBL
Affinity DataIC50: 13nMAssay Description:Inhibition of rat 11betaHSD1 assessed as reduction of cortisone to cortisol by ELISAMore data for this Ligand-Target Pair
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Hoffmann-La Roche
Curated by ChEMBL
Hoffmann-La Roche
Curated by ChEMBL
Affinity DataIC50: 9nMAssay Description:Inhibition of full-length human 11betaHSD1 expressed in HEK293 cells assessed as cortisol level by competitive ELISAMore data for this Ligand-Target Pair