BDBM50019191 1-Methyl-1H-indole-2-carboxylic acid (1-methyl-2-oxo-5-phenyl-2,3-dihydro-1H-benzo[e][1,4]diazepin-3-yl)-amide::CHEMBL71079
SMILES CN1c2ccccc2C(=NC(NC(=O)c2cc3ccccc3n2C)C1=O)c1ccccc1
InChI Key InChIKey=LORMCGPDRBOOEU-UHFFFAOYSA-N
Data 7 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 7 hits for monomerid = 50019191
Affinity DataIC50: 1.50E+4nMAssay Description:Tested for its activity to inhibit the binding of [125I]-CCK-33 to Cholecystokinin type B receptor in guinea pig brainMore data for this Ligand-Target Pair
Affinity DataIC50: 1.40nMAssay Description:Tested for its activity to inhibit the binding of [125I]-CCK-33 to Cholecystokinin type A receptor in rat pancreasMore data for this Ligand-Target Pair
Affinity DataIC50: 1.40nMAssay Description:Half-maximal inhibition of [125I]CCK-33 binding to cholecystokinin A receptor from rat pancreatic tissueMore data for this Ligand-Target Pair
Affinity DataIC50: 2.00E+3nMAssay Description:Tested for its activity to inhibit the binding of [125I]-gastrin to gastric glands (gastrin) in guinea pigMore data for this Ligand-Target Pair
Affinity DataIC50: 1.41nMAssay Description:Binding affinity against cholecystokinin type A receptor of rat pancreasMore data for this Ligand-Target Pair
TargetCholecystokinin receptor type A/Gastrin/cholecystokinin type B receptor(Homo sapiens (Human))
Merck Sharp & Dohme Research Laboratories
Curated by ChEMBL
Merck Sharp & Dohme Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 1.50E+4nMAssay Description:Half-maximal inhibition of [125I]-CCK-8(+) binding to cholecystokinin receptor from guinea pig brain tissueMore data for this Ligand-Target Pair
Affinity DataIC50: 2.00E+3nMAssay Description:Half-maximal inhibition of [125I]gastrin binding to guinea pig gastric glandsMore data for this Ligand-Target Pair