BDBM50019461 (5-Amino-1,3-dimethyl-1H-pyrazol-4-yl)-(2-fluoro-phenyl)-methanone::CHEMBL284983

SMILES: Cc1nn(C)c(N)c1C(=O)c1ccccc1F

InChI Key: InChIKey=LMBRFPRUZRLJAW-UHFFFAOYSA-N

Data: 5 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50019461   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Adenosine receptor A1 (Rattus norvegicus (rat))	BDBM50019461 ((5-Amino-1,3-dimethyl-1H-pyrazol-4-yl)-(2-fluoro-p...) Show SMILES Cc1nn(C)c(N)c1C(=O)c1ccccc1F Show InChI InChI=1S/C12H12FN3O/c1-7-10(12(14)16(2)15-7)11(17)8-5-3-4-6-9(8)13/h3-6H,14H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Binding affinity towards adenosine A1 receptor using [3H]- CHA				J Med Chem 29: 1628-37 (1986) Article DOI: 10.1021/jm00159a011 BindingDB Entry DOI: 10.7270/Q2319TVF
					More data for this Ligand-Target Pair
Adrenergic receptor alpha-2 (RAT-NEONATAL RAT-Rattus norvegicus (rat))	BDBM50019461 ((5-Amino-1,3-dimethyl-1H-pyrazol-4-yl)-(2-fluoro-p...) Show SMILES Cc1nn(C)c(N)c1C(=O)c1ccccc1F Show InChI InChI=1S/C12H12FN3O/c1-7-10(12(14)16(2)15-7)11(17)8-5-3-4-6-9(8)13/h3-6H,14H2,1-2H3	PDB Reactome pathway UniProtKB/SwissProt GoogleScholar	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Binding affinity against alpha-2 adrenergic receptor in rat brain using [3H]- clonidine				J Med Chem 29: 1628-37 (1986) Article DOI: 10.1021/jm00159a011 BindingDB Entry DOI: 10.7270/Q2319TVF
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor (RAT)	BDBM50019461 ((5-Amino-1,3-dimethyl-1H-pyrazol-4-yl)-(2-fluoro-p...) Show SMILES Cc1nn(C)c(N)c1C(=O)c1ccccc1F Show InChI InChI=1S/C12H12FN3O/c1-7-10(12(14)16(2)15-7)11(17)8-5-3-4-6-9(8)13/h3-6H,14H2,1-2H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Binding affinity against muscarinic receptor in rat brain using [3H]- QNB				J Med Chem 29: 1628-37 (1986) Article DOI: 10.1021/jm00159a011 BindingDB Entry DOI: 10.7270/Q2319TVF
					More data for this Ligand-Target Pair
Alpha-1 Adrenergic Receptor/ adrenergic receptor/ adrenergic receptor (Rattus norvegicus (rat)-Rattus norvegicus (Rat))	BDBM50019461 ((5-Amino-1,3-dimethyl-1H-pyrazol-4-yl)-(2-fluoro-p...) Show SMILES Cc1nn(C)c(N)c1C(=O)c1ccccc1F Show InChI InChI=1S/C12H12FN3O/c1-7-10(12(14)16(2)15-7)11(17)8-5-3-4-6-9(8)13/h3-6H,14H2,1-2H3	Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Binding affinity against alpha-1 adrenergic receptor in rat brain using [3H]- WB-4101				J Med Chem 29: 1628-37 (1986) Article DOI: 10.1021/jm00159a011 BindingDB Entry DOI: 10.7270/Q2319TVF
					More data for this Ligand-Target Pair
Dopamine receptor (Rattus norvegicus (rat)-RAT-Rattus norvegicus (Rat...)	BDBM50019461 ((5-Amino-1,3-dimethyl-1H-pyrazol-4-yl)-(2-fluoro-p...) Show SMILES Cc1nn(C)c(N)c1C(=O)c1ccccc1F Show InChI InChI=1S/C12H12FN3O/c1-7-10(12(14)16(2)15-7)11(17)8-5-3-4-6-9(8)13/h3-6H,14H2,1-2H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Binding affinity for dopamine receptor in rat striatal membrane using [3H]haloperidol as radioligand				J Med Chem 29: 1628-37 (1986) Article DOI: 10.1021/jm00159a011 BindingDB Entry DOI: 10.7270/Q2319TVF
					More data for this Ligand-Target Pair