BDBM50019680 2-Isopropyl-11-oxo-11H-pyrido[2,1-b]quinazoline-8-carboxylic acid (5-pyridin-3-yl-pentyl)-amide::CHEMBL1204216::CHEMBL56932

SMILES CC(C)c1ccc2nc3ccc(cn3c(=O)c2c1)C(=O)NCCCCCc1cccnc1

InChI Key InChIKey=HZJYZCBTYJYBTL-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50019680   

TargetThromboxane-A synthase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50019680(2-Isopropyl-11-oxo-11H-pyrido[2,1-b]quinazoline-8-...)
Affinity DataIC50:  100nMAssay Description:Inhibition of human platelet thromboxane synthase (TXA2) was determined in human plateletsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlatelet-activating factor receptor(Homo sapiens (Human))
Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50019680(2-Isopropyl-11-oxo-11H-pyrido[2,1-b]quinazoline-8-...)
Affinity DataIC50: >1.00E+3nMAssay Description:Ability to inhibit platelet activating factor (PAF) binding to platelets by 50% was determined by using [3H]-PAF as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed