BDBM50019904 CHEMBL3287209::US9533999, ii-1

SMILES FC(F)(F)Oc1cccc(CN2C(=O)CSc3cccnc23)c1

InChI Key InChIKey=NCPJHYQGWPFKQN-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50019904   

TargetIntermediate conductance calcium-activated potassium channel protein 4(Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM50019904(CHEMBL3287209 | US9533999, ii-1)
Affinity DataIC50:  52nMAssay Description:HEK293 cells over-expressing human KCa3.1 are used to measure the effects of compounds in inhibiting the KCa3.1 channel function. The assay is based ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetIntermediate conductance calcium-activated potassium channel protein 4(Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM50019904(CHEMBL3287209 | US9533999, ii-1)
Affinity DataIC50:  52nMAssay Description:Inhibition of human KCa3.1 overexpressed in HEK293 cells assessed as thallium influx preincubated for 15 mins followed by thallium/ionomycin addition...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed