BDBM50019904 CHEMBL3287209::US9533999, ii-1
SMILES FC(F)(F)Oc1cccc(CN2C(=O)CSc3cccnc23)c1
InChI Key InChIKey=NCPJHYQGWPFKQN-UHFFFAOYSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 50019904
TargetIntermediate conductance calcium-activated potassium channel protein 4(Homo sapiens (Human))
Boehringer Ingelheim International
US Patent
Boehringer Ingelheim International
US Patent
Affinity DataIC50: 52nMAssay Description:HEK293 cells over-expressing human KCa3.1 are used to measure the effects of compounds in inhibiting the KCa3.1 channel function. The assay is based ...More data for this Ligand-Target Pair
TargetIntermediate conductance calcium-activated potassium channel protein 4(Homo sapiens (Human))
Boehringer Ingelheim International
US Patent
Boehringer Ingelheim International
US Patent
Affinity DataIC50: 52nMAssay Description:Inhibition of human KCa3.1 overexpressed in HEK293 cells assessed as thallium influx preincubated for 15 mins followed by thallium/ionomycin addition...More data for this Ligand-Target Pair