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BDBM50020207 CHEMBL2369473::Gly-D-Ticc(-Cys-Tyr-D-Trp-Orn-Thr-Pen-)Thr-NH2

SMILES: [H][C@]1(NC(=O)[C@H](CCCN)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@@H](Cc2ccc(O)cc2)NC(=O)[C@H](CSSC(C)(C)[C@H](NC1=O)C(=O)N[C@@H]([C@@H](C)O)C(N)=O)NC(=O)[C@H]1Cc2ccccc2CN1C(=O)CN)[C@@H](C)O

InChI Key: InChIKey=ATYZDDGFJJQCCO-WGQWSGESSA-N

Data: 3 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50020207   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Opioid receptors; mu & delta


(Rattus norvegicus (rat))
BDBM50020207
PNG
(CHEMBL2369473 | Gly-D-Ticc(-Cys-Tyr-D-Trp-Orn-Thr-...)
Show SMILES C[C@@H](O)[C@H](NC(=O)[C@H]1NC(=O)[C@@H](NC(=O)[C@H](CCCN)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@@H](Cc2ccc(O)cc2)NC(=O)[C@H](CSSC1(C)C)NC(=O)[C@H]1Cc2ccccc2CN1C(=O)CN)[C@@H](C)O)C(N)=O
Show InChI InChI=1S/C53H70N12O12S2/c1-27(66)42(45(56)70)62-52(77)44-53(3,4)79-78-26-39(61-50(75)40-22-30-10-5-6-11-31(30)25-65(40)41(69)23-55)49(74)59-37(20-29-15-17-33(68)18-16-29)47(72)60-38(21-32-24-57-35-13-8-7-12-34(32)35)48(73)58-36(14-9-19-54)46(71)63-43(28(2)67)51(76)64-44/h5-8,10-13,15-18,24,27-28,36-40,42-44,57,66-68H,9,14,19-23,25-26,54-55H2,1-4H3,(H2,56,70)(H,58,73)(H,59,74)(H,60,72)(H,61,75)(H,62,77)(H,63,71)(H,64,76)/t27-,28-,36+,37-,38+,39+,40-,42+,43+,44-/m1/s1
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Article
PubMed
n/an/a 5.35E+3n/an/an/an/an/an/a



University of Arizona

Curated by ChEMBL


Assay Description
Binding affinity in competition with [3H]- DPDPE in Opioid receptor delta 1 binding to rat brain membrane


J Med Chem 31: 2170-7 (1988)


Article DOI: 10.1021/jm00119a019
BindingDB Entry DOI: 10.7270/Q2J38RJX
More data for this
Ligand-Target Pair
Somatostatin receptor


(RAT)
BDBM50020207
PNG
(CHEMBL2369473 | Gly-D-Ticc(-Cys-Tyr-D-Trp-Orn-Thr-...)
Show SMILES C[C@@H](O)[C@H](NC(=O)[C@H]1NC(=O)[C@@H](NC(=O)[C@H](CCCN)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@@H](Cc2ccc(O)cc2)NC(=O)[C@H](CSSC1(C)C)NC(=O)[C@H]1Cc2ccccc2CN1C(=O)CN)[C@@H](C)O)C(N)=O
Show InChI InChI=1S/C53H70N12O12S2/c1-27(66)42(45(56)70)62-52(77)44-53(3,4)79-78-26-39(61-50(75)40-22-30-10-5-6-11-31(30)25-65(40)41(69)23-55)49(74)59-37(20-29-15-17-33(68)18-16-29)47(72)60-38(21-32-24-57-35-13-8-7-12-34(32)35)48(73)58-36(14-9-19-54)46(71)63-43(28(2)67)51(76)64-44/h5-8,10-13,15-18,24,27-28,36-40,42-44,57,66-68H,9,14,19-23,25-26,54-55H2,1-4H3,(H2,56,70)(H,58,73)(H,59,74)(H,60,72)(H,61,75)(H,62,77)(H,63,71)(H,64,76)/t27-,28-,36+,37-,38+,39+,40-,42+,43+,44-/m1/s1
MMDB

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GoogleScholar
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PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 1.94E+4n/an/an/an/an/an/a



University of Arizona

Curated by ChEMBL


Assay Description
Binding affinity in competition with [125I]- CGP-23996 in somatostatin receptor binding to rat brain membrane


J Med Chem 31: 2170-7 (1988)


Article DOI: 10.1021/jm00119a019
BindingDB Entry DOI: 10.7270/Q2J38RJX
More data for this
Ligand-Target Pair
Nociceptin/mu opioid receptor


(Rattus norvegicus (rat))
BDBM50020207
PNG
(CHEMBL2369473 | Gly-D-Ticc(-Cys-Tyr-D-Trp-Orn-Thr-...)
Show SMILES C[C@@H](O)[C@H](NC(=O)[C@H]1NC(=O)[C@@H](NC(=O)[C@H](CCCN)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@@H](Cc2ccc(O)cc2)NC(=O)[C@H](CSSC1(C)C)NC(=O)[C@H]1Cc2ccccc2CN1C(=O)CN)[C@@H](C)O)C(N)=O
Show InChI InChI=1S/C53H70N12O12S2/c1-27(66)42(45(56)70)62-52(77)44-53(3,4)79-78-26-39(61-50(75)40-22-30-10-5-6-11-31(30)25-65(40)41(69)23-55)49(74)59-37(20-29-15-17-33(68)18-16-29)47(72)60-38(21-32-24-57-35-13-8-7-12-34(32)35)48(73)58-36(14-9-19-54)46(71)63-43(28(2)67)51(76)64-44/h5-8,10-13,15-18,24,27-28,36-40,42-44,57,66-68H,9,14,19-23,25-26,54-55H2,1-4H3,(H2,56,70)(H,58,73)(H,59,74)(H,60,72)(H,61,75)(H,62,77)(H,63,71)(H,64,76)/t27-,28-,36+,37-,38+,39+,40-,42+,43+,44-/m1/s1
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PC cid
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UniChem

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Article
PubMed
n/an/a 278n/an/an/an/an/an/a



University of Arizona

Curated by ChEMBL


Assay Description
Binding affinity in competition with [3H]- CTOP in Opioid receptor mu 1 binding to rat brain membrane


J Med Chem 31: 2170-7 (1988)


Article DOI: 10.1021/jm00119a019
BindingDB Entry DOI: 10.7270/Q2J38RJX
More data for this
Ligand-Target Pair