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BDBM50020214 CHEMBL302596::D-Phec(-Cys-Tyr-D-Trp-Lys-D-Pen-)Thr-NH2

SMILES: C[C@@H](O)[C@H](NC(=O)[C@@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccc(O)cc2)NC(=O)[C@H](CSSC1(C)C)NC(=O)[C@@H](N)Cc1ccccc1)C(N)=O

InChI Key: InChIKey=ONCSWBSXRSYNEQ-BQZJVUDQSA-N

Data: 2 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50020214   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Somatostatin receptor


(RAT)
BDBM50020214
PNG
(CHEMBL302596 | D-Phec(-Cys-Tyr-D-Trp-Lys-D-Pen-)Th...)
Show SMILES C[C@@H](O)[C@H](NC(=O)[C@@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccc(O)cc2)NC(=O)[C@H](CSSC1(C)C)NC(=O)[C@@H](N)Cc1ccccc1)C(N)=O
Show InChI InChI=1S/C47H62N10O9S2/c1-26(58)38(40(50)60)56-46(66)39-47(2,3)68-67-25-37(55-41(61)32(49)21-27-11-5-4-6-12-27)45(65)53-35(22-28-16-18-30(59)19-17-28)43(63)54-36(23-29-24-51-33-14-8-7-13-31(29)33)44(64)52-34(42(62)57-39)15-9-10-20-48/h4-8,11-14,16-19,24,26,32,34-39,51,58-59H,9-10,15,20-23,25,48-49H2,1-3H3,(H2,50,60)(H,52,64)(H,53,65)(H,54,63)(H,55,61)(H,56,66)(H,57,62)/t26-,32+,34+,35+,36+,37+,38+,39+/m1/s1
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B.MOAD
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CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 6.10E+3n/an/an/an/an/an/a



University of Arizona

Curated by ChEMBL


Assay Description
Binding affinity in competition with [125I]- CGP-23996 in somatostatin receptor binding to rat brain membrane


J Med Chem 31: 2170-7 (1988)


Article DOI: 10.1021/jm00119a019
BindingDB Entry DOI: 10.7270/Q2J38RJX
More data for this
Ligand-Target Pair
Opioid receptors; mu & delta


(Rattus norvegicus (rat))
BDBM50020214
PNG
(CHEMBL302596 | D-Phec(-Cys-Tyr-D-Trp-Lys-D-Pen-)Th...)
Show SMILES C[C@@H](O)[C@H](NC(=O)[C@@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccc(O)cc2)NC(=O)[C@H](CSSC1(C)C)NC(=O)[C@@H](N)Cc1ccccc1)C(N)=O
Show InChI InChI=1S/C47H62N10O9S2/c1-26(58)38(40(50)60)56-46(66)39-47(2,3)68-67-25-37(55-41(61)32(49)21-27-11-5-4-6-12-27)45(65)53-35(22-28-16-18-30(59)19-17-28)43(63)54-36(23-29-24-51-33-14-8-7-13-31(29)33)44(64)52-34(42(62)57-39)15-9-10-20-48/h4-8,11-14,16-19,24,26,32,34-39,51,58-59H,9-10,15,20-23,25,48-49H2,1-3H3,(H2,50,60)(H,52,64)(H,53,65)(H,54,63)(H,55,61)(H,56,66)(H,57,62)/t26-,32+,34+,35+,36+,37+,38+,39+/m1/s1
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KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a>1.00E+4n/an/an/an/an/an/a



University of Arizona

Curated by ChEMBL


Assay Description
Binding affinity in competition with [3H]- DPDPE in Opioid receptor delta 1 binding to rat brain membrane


J Med Chem 31: 2170-7 (1988)


Article DOI: 10.1021/jm00119a019
BindingDB Entry DOI: 10.7270/Q2J38RJX
More data for this
Ligand-Target Pair