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BDBM50020382 3-[2-(1-Carboxy-3-phenyl-propylamino)-propionyl]-1-methyl-2-oxo-imidazolidine-4-carboxylic acid::CHEMBL99701::Imidaprilat

SMILES: C[C@H](N[C@@H](CCc1ccccc1)C(O)=O)C(=O)N1[C@@H](CN(C)C1=O)C(O)=O

InChI Key: InChIKey=VFAVNRVDTAPBNR-UBHSHLNASA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50020382   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Angiotensin-converting enzyme


(Homo sapiens (human))
BDBM50020382
PNG
(3-[2-(1-Carboxy-3-phenyl-propylamino)-propionyl]-1...)
Show SMILES C[C@H](N[C@@H](CCc1ccccc1)C(O)=O)C(=O)N1[C@@H](CN(C)C1=O)C(O)=O
Show InChI InChI=1S/C18H23N3O6/c1-11(15(22)21-14(17(25)26)10-20(2)18(21)27)19-13(16(23)24)9-8-12-6-4-3-5-7-12/h3-7,11,13-14,19H,8-10H2,1-2H3,(H,23,24)(H,25,26)/t11-,13-,14-/m0/s1
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Similars

Article
PubMed
n/an/a 1.70n/an/an/an/an/an/a



Tanabe Seiyaku Co., Ltd.

Curated by ChEMBL


Assay Description
Inhibition of Angiotensin I converting enzyme from pig renal cortex, hippuryl-histidyl-leucine as substrate


J Med Chem 32: 289-97 (1989)


Article DOI: 10.1021/jm00122a003
BindingDB Entry DOI: 10.7270/Q2XP75JS
More data for this
Ligand-Target Pair