BDBM50020581 2-Iodo-4-{2-[4-(3-trifluoromethyl-phenyl)-piperazin-1-yl]-ethyl}-phenylamine::CHEMBL153174

SMILES Nc1ccc(CCN2CCN(CC2)c2cccc(c2)C(F)(F)F)cc1I

InChI Key InChIKey=SRQUFBCRUHYBHN-UHFFFAOYSA-N

Data  2 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50020581   

Target5-hydroxytryptamine receptor 1A(Human)
University of Pennsylvania

Curated by ChEMBL
LigandPNGBDBM50020581(CHEMBL153174 | 2-Iodo-4-{2-[4-(3-trifluoromethyl-p...)
Affinity DataKi:  19nMAssay Description:In vitro inhibition of [3H]5-HT (2 nM) binding to 5-hydroxytryptamine 1A receptor from bovine hippocampusMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
University of Pennsylvania

Curated by ChEMBL
LigandPNGBDBM50020581(CHEMBL153174 | 2-Iodo-4-{2-[4-(3-trifluoromethyl-p...)
Affinity DataKi:  20nMAssay Description:In vitro inhibition of [3H]DPAT (1 nM) binding to 5-hydroxytryptamine 1A receptor from bovine hippocampusMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
University of Pennsylvania

Curated by ChEMBL
LigandPNGBDBM50020581(CHEMBL153174 | 2-Iodo-4-{2-[4-(3-trifluoromethyl-p...)
Affinity DataIC50: 38nMAssay Description:In vitro inhibition of [3H]DPAT (1 nM) binding to 5-HT1A receptor from bovine hippocampusMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
University of Pennsylvania

Curated by ChEMBL
LigandPNGBDBM50020581(CHEMBL153174 | 2-Iodo-4-{2-[4-(3-trifluoromethyl-p...)
Affinity DataIC50: 40nMAssay Description:In vitro inhibition of [3H]5-HT (2 nM) binding to 5-hydroxytryptamine 1A receptor from bovine hippocampusMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed