BDBM50020680 4-[2-(dipropylamino)ethyl]-1,3-dihydro-2H-indol-2-one::CHEMBL589::ROPINIROLE

SMILES: CCCN(CCC)CCc1cccc2NC(=O)Cc12

InChI Key: InChIKey=UHSKFQJFRQCDBE-UHFFFAOYSA-N

Data: 53 KI  3 IC50  17 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 73 hits for monomerid = 50020680   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
D(3) dopamine receptor (Human)	BDBM50020680 (CHEMBL589 | 4-[2-(dipropylamino)ethyl]-1,3-dihydro...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	100	n/a	n/a	n/a	n/a
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D(2) dopamine receptor (Human)	BDBM50020680 (CHEMBL589 | 4-[2-(dipropylamino)ethyl]-1,3-dihydro...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	330	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
D(2) dopamine receptor (Human)	BDBM50020680 (CHEMBL589 | 4-[2-(dipropylamino)ethyl]-1,3-dihydro...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	30	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
D(2) dopamine receptor (Human)	BDBM50020680 (CHEMBL589 | 4-[2-(dipropylamino)ethyl]-1,3-dihydro...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	89	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
D(2) dopamine receptor (Human)	BDBM50020680 (CHEMBL589 | 4-[2-(dipropylamino)ethyl]-1,3-dihydro...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	330	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Human)	BDBM50020680 (CHEMBL589 | 4-[2-(dipropylamino)ethyl]-1,3-dihydro...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	89	n/a	n/a	n/a	n/a
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D(2) dopamine receptor (Bovine)	BDBM50020680 (CHEMBL589 | 4-[2-(dipropylamino)ethyl]-1,3-dihydro...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	6.81E+3	n/a	n/a	n/a	n/a	n/a	n/a
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D(2) dopamine receptor (Rat)	BDBM50020680 (CHEMBL589 | 4-[2-(dipropylamino)ethyl]-1,3-dihydro...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
D(3) dopamine receptor (Rat)	BDBM50020680 (CHEMBL589 | 4-[2-(dipropylamino)ethyl]-1,3-dihydro...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	107	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rat)	BDBM50020680 (CHEMBL589 | 4-[2-(dipropylamino)ethyl]-1,3-dihydro...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	76	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Human)	BDBM50020680 (CHEMBL589 | 4-[2-(dipropylamino)ethyl]-1,3-dihydro...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	83	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
D(3) dopamine receptor (Human)	BDBM50020680 (CHEMBL589 | 4-[2-(dipropylamino)ethyl]-1,3-dihydro...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	4	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Human)	BDBM50020680 (CHEMBL589 | 4-[2-(dipropylamino)ethyl]-1,3-dihydro...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	304	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
D(3) dopamine receptor (Human)	BDBM50020680 (CHEMBL589 | 4-[2-(dipropylamino)ethyl]-1,3-dihydro...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	19.2	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Human)	BDBM50020680 (CHEMBL589 | 4-[2-(dipropylamino)ethyl]-1,3-dihydro...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	304	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
D(3) dopamine receptor (Human)	BDBM50020680 (CHEMBL589 | 4-[2-(dipropylamino)ethyl]-1,3-dihydro...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	10.3	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Human)	BDBM50020680 (CHEMBL589 | 4-[2-(dipropylamino)ethyl]-1,3-dihydro...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	304	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
D(3) dopamine receptor (Human)	BDBM50020680 (CHEMBL589 | 4-[2-(dipropylamino)ethyl]-1,3-dihydro...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	10.3	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Human)	BDBM50020680 (CHEMBL589 | 4-[2-(dipropylamino)ethyl]-1,3-dihydro...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	304	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Human)	BDBM50020680 (CHEMBL589 | 4-[2-(dipropylamino)ethyl]-1,3-dihydro...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	302	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Human)	BDBM50020680 (CHEMBL589 | 4-[2-(dipropylamino)ethyl]-1,3-dihydro...) Show SMILES Show InChI	GoogleScholar	UniChem		7.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
D(3) dopamine receptor (Human)	BDBM50020680 (CHEMBL589 | 4-[2-(dipropylamino)ethyl]-1,3-dihydro...) Show SMILES Show InChI	GoogleScholar	UniChem		19	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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D(3) dopamine receptor (Rat)	BDBM50020680 (CHEMBL589 | 4-[2-(dipropylamino)ethyl]-1,3-dihydro...) Show SMILES Show InChI	GoogleScholar	UniChem		29.3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
D(3) dopamine receptor (Human)	BDBM50020680 (CHEMBL589 | 4-[2-(dipropylamino)ethyl]-1,3-dihydro...) Show SMILES Show InChI	GoogleScholar	UniChem		36.3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
D(3) dopamine receptor (Human)	BDBM50020680 (CHEMBL589 | 4-[2-(dipropylamino)ethyl]-1,3-dihydro...) Show SMILES Show InChI	GoogleScholar	UniChem		37.1	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
D(3) dopamine receptor (Human)	BDBM50020680 (CHEMBL589 | 4-[2-(dipropylamino)ethyl]-1,3-dihydro...) Show SMILES Show InChI	GoogleScholar	UniChem		37.1	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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5-hydroxytryptamine receptor 1A (Human)	BDBM50020680 (CHEMBL589 | 4-[2-(dipropylamino)ethyl]-1,3-dihydro...) Show SMILES Show InChI	GoogleScholar	UniChem		288	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Human)	BDBM50020680 (CHEMBL589 | 4-[2-(dipropylamino)ethyl]-1,3-dihydro...) Show SMILES Show InChI	GoogleScholar	UniChem		676	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Human)	BDBM50020680 (CHEMBL589 | 4-[2-(dipropylamino)ethyl]-1,3-dihydro...) Show SMILES Show InChI	GoogleScholar	UniChem		676	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Human)	BDBM50020680 (CHEMBL589 | 4-[2-(dipropylamino)ethyl]-1,3-dihydro...) Show SMILES Show InChI	GoogleScholar	UniChem		692	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Alpha-2B adrenergic receptor (Human)	BDBM50020680 (CHEMBL589 | 4-[2-(dipropylamino)ethyl]-1,3-dihydro...) Show SMILES Show InChI	GoogleScholar	UniChem		759	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Alpha-2B adrenergic receptor (Human)	BDBM50020680 (CHEMBL589 | 4-[2-(dipropylamino)ethyl]-1,3-dihydro...) Show SMILES Show InChI	GoogleScholar	UniChem		759	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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D(4) dopamine receptor (Human)	BDBM50020680 (CHEMBL589 | 4-[2-(dipropylamino)ethyl]-1,3-dihydro...) Show SMILES Show InChI	GoogleScholar	UniChem		851	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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D(4) dopamine receptor (Human)	BDBM50020680 (CHEMBL589 | 4-[2-(dipropylamino)ethyl]-1,3-dihydro...) Show SMILES Show InChI	GoogleScholar	UniChem		851	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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D(4) dopamine receptor (Human)	BDBM50020680 (CHEMBL589 | 4-[2-(dipropylamino)ethyl]-1,3-dihydro...) Show SMILES Show InChI	GoogleScholar	UniChem		873	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Human)	BDBM50020680 (CHEMBL589 | 4-[2-(dipropylamino)ethyl]-1,3-dihydro...) Show SMILES Show InChI	GoogleScholar	UniChem		933	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Human)	BDBM50020680 (CHEMBL589 | 4-[2-(dipropylamino)ethyl]-1,3-dihydro...) Show SMILES Show InChI	GoogleScholar	UniChem		933	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rat)	BDBM50020680 (CHEMBL589 | 4-[2-(dipropylamino)ethyl]-1,3-dihydro...) Show SMILES Show InChI	GoogleScholar	UniChem		1.15E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Alpha-2C adrenergic receptor (Human)	BDBM50020680 (CHEMBL589 | 4-[2-(dipropylamino)ethyl]-1,3-dihydro...) Show SMILES Show InChI	GoogleScholar	UniChem		1.20E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Alpha-2C adrenergic receptor (Human)	BDBM50020680 (CHEMBL589 | 4-[2-(dipropylamino)ethyl]-1,3-dihydro...) Show SMILES Show InChI	GoogleScholar	UniChem		1.20E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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5-hydroxytryptamine receptor 1D (Human)	BDBM50020680 (CHEMBL589 | 4-[2-(dipropylamino)ethyl]-1,3-dihydro...) Show SMILES Show InChI	GoogleScholar	UniChem		1.38E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1D (Human)	BDBM50020680 (CHEMBL589 | 4-[2-(dipropylamino)ethyl]-1,3-dihydro...) Show SMILES Show InChI	GoogleScholar	UniChem		1.38E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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5-hydroxytryptamine receptor 7 (Human)	BDBM50020680 (CHEMBL589 | 4-[2-(dipropylamino)ethyl]-1,3-dihydro...) Show SMILES Show InChI	GoogleScholar	UniChem		1.51E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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5-hydroxytryptamine receptor 1A (Human)	BDBM50020680 (CHEMBL589 | 4-[2-(dipropylamino)ethyl]-1,3-dihydro...) Show SMILES Show InChI	GoogleScholar	UniChem		1.71E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Alpha-2A adrenergic receptor (Human)	BDBM50020680 (CHEMBL589 | 4-[2-(dipropylamino)ethyl]-1,3-dihydro...) Show SMILES Show InChI	GoogleScholar	UniChem		1.86E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Alpha-2A adrenergic receptor (Human)	BDBM50020680 (CHEMBL589 | 4-[2-(dipropylamino)ethyl]-1,3-dihydro...) Show SMILES Show InChI	GoogleScholar	UniChem		1.86E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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D(2) dopamine receptor (Rat)	BDBM50020680 (CHEMBL589 | 4-[2-(dipropylamino)ethyl]-1,3-dihydro...) Show SMILES Show InChI	GoogleScholar	UniChem		2.67E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Histamine H1 receptor (Guinea pig)	BDBM50020680 (CHEMBL589 | 4-[2-(dipropylamino)ethyl]-1,3-dihydro...) Show SMILES Show InChI	GoogleScholar	UniChem		2.95E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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5-hydroxytryptamine receptor 2B (Human)	BDBM50020680 (CHEMBL589 | 4-[2-(dipropylamino)ethyl]-1,3-dihydro...) Show SMILES Show InChI	GoogleScholar	UniChem		3.80E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2B (Human)	BDBM50020680 (CHEMBL589 | 4-[2-(dipropylamino)ethyl]-1,3-dihydro...) Show SMILES Show InChI	GoogleScholar	UniChem		3.80E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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