BDBM50021398 CHEBI:18088::FORMONONETIN::NSC-93360

SMILES COc1ccc(cc1)-c1coc2cc(O)ccc2c1=O

InChI Key InChIKey=HKQYGTCOTHHOMP-UHFFFAOYSA-N

Data  1 KI  14 IC50  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 16 hits for monomerid = 50021398   

TargetCytochrome P450 1B1(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50021398(CHEBI:18088 | FORMONONETIN | NSC-93360)
Affinity DataKi:  3.70E+3nMAssay Description:Inhibition of CYP1B1 in human liver microsomes coexpressing recombinant human cytochrome P450 oxidoreductase using 7-ethoxyresorufin as substrate aft...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 1A1(Homo sapiens (Human))
University Of Nottingham

Curated by ChEMBL
LigandPNGBDBM50021398(CHEBI:18088 | FORMONONETIN | NSC-93360)
Affinity DataIC50: <1.00E+5nMAssay Description:Inhibition of CYP1A1 by EROD assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuraminidase(Influenza A virus)
Peking Union Medical College

Curated by ChEMBL
LigandPNGBDBM50021398(CHEBI:18088 | FORMONONETIN | NSC-93360)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of Influenza A PR/8/34 H1N1 virus neuraminidase activity by MUN-ANA substrate based fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuraminidase(Influenza A virus)
Peking Union Medical College

Curated by ChEMBL
LigandPNGBDBM50021398(CHEBI:18088 | FORMONONETIN | NSC-93360)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of Influenza A Jinan/15/90 H3N2 virus neuraminidase activity by MUN-ANA substrate based fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuraminidase(Influenza A virus)
Peking Union Medical College

Curated by ChEMBL
LigandPNGBDBM50021398(CHEBI:18088 | FORMONONETIN | NSC-93360)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of Influenza A Jiangsu/10/2003 virus neuraminidase activity by MUN-ANA substrate based fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuraminidase(Influenza A virus)
Peking Union Medical College

Curated by ChEMBL
LigandPNGBDBM50021398(CHEBI:18088 | FORMONONETIN | NSC-93360)
Affinity DataIC50:  5.04E+3nMAssay Description:Inhibition of oseltamivir-resistant Influenza A virus H1N1 B/55/08 neuraminidase by chemiluminescence based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProteasome subunit beta type-5(Homo sapiens (Human))
Institute Of Agricultural And Food Biotechnology

Curated by ChEMBL
LigandPNGBDBM50021398(CHEBI:18088 | FORMONONETIN | NSC-93360)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of chymotrypsin-like activity of purified human erythrocyte 20S proteasome assessed as decrease in AMC hydrolysis using Suc-LLVY-AMC as su...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuraminidase(Influenza A virus)
Peking Union Medical College

Curated by ChEMBL
LigandPNGBDBM50021398(CHEBI:18088 | FORMONONETIN | NSC-93360)
Affinity DataIC50:  1.37E+3nMAssay Description:Inhibition of Influenza A virus (A/Puerto Rico/8/1934(H1N1)) neuraminidase by chemiluminescence based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuraminidase(Influenza A virus)
Peking Union Medical College

Curated by ChEMBL
LigandPNGBDBM50021398(CHEBI:18088 | FORMONONETIN | NSC-93360)
Affinity DataIC50:  5.04E+3nMAssay Description:Inhibition of Influenza A virus (A/Hong Kong/1/1968(H3N2)) neuraminidase by chemiluminescence based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUrease subunit beta(Helicobacter pylori (strain ATCC 700392 / 26695) (...)
Jishou University

Curated by ChEMBL
LigandPNGBDBM50021398(CHEBI:18088 | FORMONONETIN | NSC-93360)
Affinity DataIC50:  2.00E+6nMAssay Description:Inhibition of Helicobacter pylori ATCC 43504 urease-mediated ammonia production preincubated for 1.5 hrs by indophenol methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmine oxidase [flavin-containing] B(Homo sapiens (Human))
Sunchon National University

Curated by ChEMBL
LigandPNGBDBM50021398(CHEBI:18088 | FORMONONETIN | NSC-93360)
Affinity DataIC50:  2.58E+4nMAssay Description:Inhibition of recombinant human MAO-B expressed in baculovirus infected BTI insect cells preincubated for 10 mins followed by addition of benzylamine...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmine oxidase [flavin-containing] A(Homo sapiens (Human))
Sunchon National University

Curated by ChEMBL
LigandPNGBDBM50021398(CHEBI:18088 | FORMONONETIN | NSC-93360)
Affinity DataIC50:  3.12E+4nMAssay Description:Inhibition of recombinant human MAO-A expressed in baculovirus infected BTI insect cells preincubated for 10 mins followed by addition of kynuramine ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmine oxidase [flavin-containing] A(Mus musculus)
Sunchon National University

Curated by ChEMBL
LigandPNGBDBM50021398(CHEBI:18088 | FORMONONETIN | NSC-93360)
Affinity DataIC50:  2.12E+4nMAssay Description:Inhibition of mouse MAO-A preincubated for 15 mins followed by addition of kynuramine as substrate measured after 30 mins by fluorometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmine oxidase [flavin-containing] B(Mus musculus)
Sunchon National University

Curated by ChEMBL
LigandPNGBDBM50021398(CHEBI:18088 | FORMONONETIN | NSC-93360)
Affinity DataIC50:  1.10E+4nMAssay Description:Inhibition of mouse MAO-B preincubated for 15 mins followed by addition of kynuramine as substrate measured after 30 mins by fluorometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterleukin-2(Homo sapiens (Human))
The Second People's Hospital of Fujian Provinc

Curated by ChEMBL
LigandPNGBDBM50021398(CHEBI:18088 | FORMONONETIN | NSC-93360)
Affinity DataKd:  5.47E+3nMAssay Description:Binding affinity to IL-2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuraminidase(Influenza A virus)
Peking Union Medical College

Curated by ChEMBL
LigandPNGBDBM50021398(CHEBI:18088 | FORMONONETIN | NSC-93360)
Affinity DataIC50:  3.04E+3nMAssay Description:Inhibition of Influenza A virus J/8178/09 neuraminidase by chemiluminescence based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed