BDBM50021437 5-Ethyl-5-phenylbarbituric acid::5-Phenyl-5-ethylbarbituric acid::5-ethyl-5-phenyl-2,4,6(1H,3H,5H)-pyrimidinetrione::5-ethyl-5-phenylpyrimidine-2,4,6(1H,3H,5H)-trione::CHEMBL40::Phenobarbital::Phenobarbitol::Phenobarbitone::Phenobarbituric Acid::Phenylaethylbarbitursaeure::Phenylethylbarbiturate::Phenylethylbarbituric Acid::Phenylethylbarbitursaeure

SMILES CCC1(C(=O)NC(=O)NC1=O)c1ccccc1

InChI Key InChIKey=DDBREPKUVSBGFI-UHFFFAOYSA-N

Data  6 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50021437   

TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Tcg Lifesciences

Curated by ChEMBL
LigandPNGBDBM50021437(5-Ethyl-5-phenylbarbituric acid | 5-Phenyl-5-ethyl...)
Affinity DataIC50:  3.02E+6nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Tcg Lifesciences

Curated by ChEMBL
LigandPNGBDBM50021437(5-Ethyl-5-phenylbarbituric acid | 5-Phenyl-5-ethyl...)
Affinity DataIC50:  3.00E+6nMAssay Description:Inhibitory concentration against IKr potassium channelMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium channel protein type 1/2/3 subunit alpha(Rattus norvegicus)
Howard University

Curated by ChEMBL
LigandPNGBDBM50021437(5-Ethyl-5-phenylbarbituric acid | 5-Phenyl-5-ethyl...)
Affinity DataIC50:  2.50E+3nMAssay Description:Inhibition of [3H]BTX-B binding to neurotoxin site 2 of sodium channel of rat cerebral cortex synaptoneurosomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium channel protein type 1/2/3 subunit alpha(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50021437(5-Ethyl-5-phenylbarbituric acid | 5-Phenyl-5-ethyl...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of [3H]-BTX binding to guinea pig voltage-dependent sodium channelMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBile salt export pump(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50021437(5-Ethyl-5-phenylbarbituric acid | 5-Phenyl-5-ethyl...)
Affinity DataIC50: >1.35E+5nMAssay Description:Inhibition of human BSEP expressed in fall armyworm sf9 cell plasma membrane vesicles assessed as reduction in vesicle-associated [3H]-taurocholate t...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Tcg Lifesciences

Curated by ChEMBL
LigandPNGBDBM50021437(5-Ethyl-5-phenylbarbituric acid | 5-Phenyl-5-ethyl...)
Affinity DataIC50:  3.02E+6nMAssay Description:Inhibition of human ERG channel in HEK293 cells by voltage-clamp methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed