BDBM50021536 CHEMBL3290576

SMILES CN1CCN(CC1)c1nc(N)nc(n1)-c1ccc(Cl)cc1

InChI Key InChIKey=WWJYDYWCKUZUPY-UHFFFAOYSA-N

Data  3 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50021536   

TargetHistamine H4 receptor(Homo sapiens (Human))
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50021536(CHEMBL3290576)
Affinity DataKi:  203nMAssay Description:Displacement of [3H]-histamine from human histamine H4 receptor expressed in insect Sf9 cell membrane co-expressing Galphai2/Gbeta1gamma2 subunits af...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Jagiellonian University

Curated by ChEMBL
LigandPNGBDBM50021536(CHEMBL3290576)
Affinity DataKi:  2.71E+3nMAssay Description:Displacement of [3H]-LSD from human 5-HT6R expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50021536(CHEMBL3290576)
Affinity DataKi:  1.32E+4nMAssay Description:Displacement of [3H]-Nalpha-methylhistamine from human histamine H3 receptor expressed in HEK293 cell membrane after 90 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H4 receptor(Homo sapiens (Human))
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50021536(CHEMBL3290576)
Affinity DataIC50:  512nMAssay Description:Antagonist activity at human histamine H4 receptor expressed in gamma-irradiated recombinant CHO cells assessed as inhibition of forskolin/histamine-...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed