BDBM50021720 CHEMBL3298983

SMILES C[C@@H](NC(=O)N1CCc2cnc(NC3CCOCC3)nc2C1)c1ccc2cc[nH]c2c1

InChI Key InChIKey=WQZCQSZZPWAGRX-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50021720   

TargetMitogen-activated protein kinase 1(Human)
Array Biopharma

Curated by ChEMBL
LigandPNGBDBM50021720(CHEMBL3298983)
Affinity DataIC50: 2nMAssay Description:Inhibition of human recombinant N-terminal 6-His-tagged ERK2 expressed in Escherichia coli using S/T17 as substrate after 30 mins by spectrophotometr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/12/2015
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 1(Human)
Array Biopharma

Curated by ChEMBL
LigandPNGBDBM50021720(CHEMBL3298983)
Affinity DataIC50: 21nMAssay Description:Inhibition of ERK2 in human HepG2 cells assessed as P90RSK phosphorylation at Ser380 after 1.5 hrs by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/12/2015
Entry Details Article
PubMed
TargetCyclin-dependent kinase 2(Human)
Array Biopharma

Curated by ChEMBL
LigandPNGBDBM50021720(CHEMBL3298983)
Affinity DataIC50: 69nMAssay Description:Inhibition of Cdk2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/12/2015
Entry Details Article
PubMed