BDBM50021812 2,6-Dichloro-N-imidazolidin-2-ylidene-benzene-1,4-diamine::2,6-Dichloro-N-imidazolidin-2-ylidene-benzene-1,4-diamine (p-aminoclonidine)::2,6-Dichloro-N-imidazolidin-2-ylidene-benzene-1,4-diamine(p-Aminoclonidine)::APRACLONIDINE::CHEMBL647::P-AMINOCLONIDINE2,6-Dichloro-N-imidazolidin-2-ylidene-benzene-1,4-diamine

SMILES [#7]-c1cc(Cl)c(\[#7]=[#6]-2\[#7]-[#6]-[#6]-[#7]-2)c(Cl)c1

InChI Key InChIKey=IEJXVRYNEISIKR-UHFFFAOYSA-N

Data  3 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50021812   

TargetAlpha-2A adrenergic receptor(Homo sapiens (Human))
Allergan

Curated by ChEMBL
LigandPNGBDBM50021812(2,6-Dichloro-N-imidazolidin-2-ylidene-benzene-1,4-...)
Affinity DataKi:  2.90nMAssay Description:Compound was tested in vitro for binding affinity against Alpha-2A adrenergic receptor from cloned human C-10 receptor transfected into Chinese hamst...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-2B adrenergic receptor(NEONATAL RAT)
Allergan

Curated by ChEMBL
LigandPNGBDBM50021812(2,6-Dichloro-N-imidazolidin-2-ylidene-benzene-1,4-...)
Affinity DataKi:  4.80nMAssay Description:Compound was tested in vitro for binding affinity against Alpha-2B adrenergic receptor from cloned rat RNG receptor transfected into Chinese hamster ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-2C adrenergic receptor(Homo sapiens (Human))
Allergan

Curated by ChEMBL
LigandPNGBDBM50021812(2,6-Dichloro-N-imidazolidin-2-ylidene-benzene-1,4-...)
Affinity DataKi:  30nMAssay Description:Compound was tested in vitro for binding affinity against Alpha-2C adrenergic receptor from cloned human C-2 receptor transfected into Chinese hamste...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-2A/Alpha-2B/Alpha-2C adrenergic receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50021812(2,6-Dichloro-N-imidazolidin-2-ylidene-benzene-1,4-...)
Affinity DataIC50:  4nMAssay Description:Inhibition of [3H]p-aminoclonidine (PAC) binding to alpha-2 adrenergic receptor of purified human platelet plasma membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed