BDBM50021887 6-(4-Methylsulfanyl-phenyl)-1,2,3,5,6,10b-hexahydro-pyrrolo[2,1-a]isoquinoline::6-(4-Methylsulfanyl-phenyl)-1,2,3,5,6,10b-hexahydro-pyrrolo[2,1-a]isoquinoline;HClO4::CHEMBL34990

SMILES CSc1ccc(cc1)[C@@H]1CN2CCC[C@@H]2c2ccccc12

InChI Key InChIKey=YVKDUIAAPBKHMJ-UHFFFAOYSA-N

Data  18 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 18 hits for monomerid = 50021887   

LigandPNGBDBM50021887(CHEMBL34990 | 6-(4-Methylsulfanyl-phenyl)-1,2,3,5,...)
Affinity DataKi:  0.620nMAssay Description:Inhibition the uptake of tritiated serotonin (5-HT) by the serotonin transporter SERT in rat synaptosomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2012
Entry Details Article
PubMed
TargetTransporter(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50021887(CHEMBL34990 | 6-(4-Methylsulfanyl-phenyl)-1,2,3,5,...)
Affinity DataKi:  3nMAssay Description:Inhibition of uptake of tritiated norepinephrine (NE) in rat synaptosomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2012
Entry Details Article
PubMed
LigandPNGBDBM50021887(CHEMBL34990 | 6-(4-Methylsulfanyl-phenyl)-1,2,3,5,...)
Affinity DataKi:  41.2nMAssay Description:Inhibition of the uptake of tritiated dopamine (DA) in rat synaptosomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2012
Entry Details Article
PubMed
LigandPNGBDBM50021887(CHEMBL34990 | 6-(4-Methylsulfanyl-phenyl)-1,2,3,5,...)
Affinity DataKi:  58nMAssay Description:Inhibition the uptake of tritiated serotonin (5-HT) by the serotonin transporter SERT in rat synaptosomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2012
Entry Details Article
PubMed
LigandPNGBDBM50021887(CHEMBL34990 | 6-(4-Methylsulfanyl-phenyl)-1,2,3,5,...)
Affinity DataKi:  58.4nMAssay Description:Inhibition the uptake of tritiated serotonin (5-HT) by the serotonin transporter SERT in rat synaptosomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2012
Entry Details Article
PubMed
TargetSerotonin 2 (5-HT2) receptor(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50021887(CHEMBL34990 | 6-(4-Methylsulfanyl-phenyl)-1,2,3,5,...)
Affinity DataKi:  208nMAssay Description:Binding affinity towards 5-hydroxytryptamine 2 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2012
Entry Details Article
PubMed
LigandPNGBDBM50021887(CHEMBL34990 | 6-(4-Methylsulfanyl-phenyl)-1,2,3,5,...)
Affinity DataKi:  213nMAssay Description:Binding affinity towards alpha-1 adrenergic receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2012
Entry Details Article
PubMed
LigandPNGBDBM50021887(CHEMBL34990 | 6-(4-Methylsulfanyl-phenyl)-1,2,3,5,...)
Affinity DataKi:  213nMAssay Description:Binding affinity towards alpha-1 adrenergic receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2012
Entry Details Article
PubMed
TargetTransporter(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50021887(CHEMBL34990 | 6-(4-Methylsulfanyl-phenyl)-1,2,3,5,...)
Affinity DataKi:  280nMAssay Description:Inhibition of uptake of tritiated norepinephrine (NE) in rat synaptosomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2012
Entry Details Article
PubMed
TargetTransporter(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50021887(CHEMBL34990 | 6-(4-Methylsulfanyl-phenyl)-1,2,3,5,...)
Affinity DataKi:  280nMAssay Description:Inhibition of uptake of tritiated norepinephrine (NE) in rat synaptosomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2012
Entry Details Article
PubMed
LigandPNGBDBM50021887(CHEMBL34990 | 6-(4-Methylsulfanyl-phenyl)-1,2,3,5,...)
Affinity DataKi:  314nMAssay Description:Binding affinity towards alpha-1 adrenergic receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2012
Entry Details Article
PubMed
LigandPNGBDBM50021887(CHEMBL34990 | 6-(4-Methylsulfanyl-phenyl)-1,2,3,5,...)
Affinity DataKi:  775nMAssay Description:Binding affinity towards serotonin S1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2012
Entry Details Article
PubMed
LigandPNGBDBM50021887(CHEMBL34990 | 6-(4-Methylsulfanyl-phenyl)-1,2,3,5,...)
Affinity DataKi:  775nMAssay Description:Binding affinity towards serotonin S1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2012
Entry Details Article
PubMed
TargetSerotonin 2 (5-HT2) receptor(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50021887(CHEMBL34990 | 6-(4-Methylsulfanyl-phenyl)-1,2,3,5,...)
Affinity DataKi:  939nMAssay Description:Binding affinity towards 5-hydroxytryptamine 2 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2012
Entry Details Article
PubMed
TargetSerotonin 2 (5-HT2) receptor(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50021887(CHEMBL34990 | 6-(4-Methylsulfanyl-phenyl)-1,2,3,5,...)
Affinity DataKi:  939nMAssay Description:Binding affinity towards 5-hydroxytryptamine 2 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2012
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50021887(CHEMBL34990 | 6-(4-Methylsulfanyl-phenyl)-1,2,3,5,...)
Affinity DataKi:  1.03E+3nMAssay Description:Binding affinity towards Dopamine receptor D2More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2012
Entry Details Article
PubMed
LigandPNGBDBM50021887(CHEMBL34990 | 6-(4-Methylsulfanyl-phenyl)-1,2,3,5,...)
Affinity DataKi:  1.45E+3nMAssay Description:Inhibition of the uptake of tritiated dopamine (DA) in rat synaptosomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2012
Entry Details Article
PubMed
LigandPNGBDBM50021887(CHEMBL34990 | 6-(4-Methylsulfanyl-phenyl)-1,2,3,5,...)
Affinity DataKi:  1.45E+3nMAssay Description:Inhibition of the uptake of tritiated dopamine (DA) in rat synaptosomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2012
Entry Details Article
PubMed