BDBM50021925 2-Ethyl-4-phenyl-1,2,3,4-tetrahydro-isoquinoline::CHEMBL286455

SMILES CCN1CC(c2ccccc2)c2ccccc2C1

InChI Key InChIKey=QKUVNSGJPHVOHY-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50021925   

TargetTransporter(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50021925(CHEMBL286455 | 2-Ethyl-4-phenyl-1,2,3,4-tetrahydro...)
Affinity DataKi:  5.60nMAssay Description:Inhibition of uptake of tritiated norepinephrine (NE) in rat synaptosomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2012
Entry Details Article
PubMed
LigandPNGBDBM50021925(CHEMBL286455 | 2-Ethyl-4-phenyl-1,2,3,4-tetrahydro...)
Affinity DataKi:  36nMAssay Description:Inhibition of the uptake of tritiated dopamine (DA) in rat synaptosomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2012
Entry Details Article
PubMed
LigandPNGBDBM50021925(CHEMBL286455 | 2-Ethyl-4-phenyl-1,2,3,4-tetrahydro...)
Affinity DataKi:  170nMAssay Description:Inhibition the uptake of tritiated serotonin (5-HT) by the serotonin transporter SERT in rat synaptosomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2012
Entry Details Article
PubMed