BDBM50021954 (2S,5R)-3,3-Dimethyl-4,4,7-trioxo-4lambda*6*-thia-1-aza-bicyclo[3.2.0]heptane-2-carboxylic acid::(S)-3,3-Dimethyl-7-(R)-oxo-4,4-dioxo-4lambda*6*-thia-1-aza-bicyclo[3.2.0]heptane-2-carboxylic acid::3,3-Dimethyl-4,4,7-trioxo-4lambda*6*-thia-1-aza-bicyclo[3.2.0]heptane-2-carboxylic acid::3,3-Dimethyl-4,4,7-trioxo-4lambda*6*-thia-1-aza-bicyclo[3.2.0]heptane-2-carboxylic acid (Sulbactam)::CHEMBL403::CP-45,899::SULBACTAM::UNASYN::US20230322715, Compound ALK-09::US9120808, Sulbactam sodium salt

SMILES: CC1([C@@H](N2[C@H](S1(=O)=O)CC2=O)C(=O)O)C

InChI Key: InChIKey=FKENQMMABCRJMK-UHFFFAOYSA-N

Data: 3 KI  54 IC50

PDB links: 3 PDB IDs match this monomer.

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 56 hits for monomerid = 50021954   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Beta-lactamase (Escherichia coli)	BDBM50021954 (UNASYN | 3,3-Dimethyl-4,4,7-trioxo-4lambda*6*-thia...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	6.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Beta-lactamase 1 (Bacillus cereus)	BDBM50021954 (UNASYN | 3,3-Dimethyl-4,4,7-trioxo-4lambda*6*-thia...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Beta-lactamase 1 (Bacillus cereus)	BDBM50021954 (UNASYN | 3,3-Dimethyl-4,4,7-trioxo-4lambda*6*-thia...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Beta-lactamase TEM (Escherichia coli)	BDBM50021954 (UNASYN | 3,3-Dimethyl-4,4,7-trioxo-4lambda*6*-thia...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	800	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Beta-lactamase (Enterobacter cloacae)	BDBM50021954 (UNASYN | 3,3-Dimethyl-4,4,7-trioxo-4lambda*6*-thia...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Beta-lactamase (Pseudomonas aeruginosa)	BDBM50021954 (UNASYN | 3,3-Dimethyl-4,4,7-trioxo-4lambda*6*-thia...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	370	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Class D beta-lactamase (Brachyspira pilosicoli)	BDBM50021954 (UNASYN | 3,3-Dimethyl-4,4,7-trioxo-4lambda*6*-thia...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.20E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Beta-lactamase (Escherichia coli)	BDBM50021954 (UNASYN | 3,3-Dimethyl-4,4,7-trioxo-4lambda*6*-thia...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Beta-lactamase (Acinetobacter genomosp. 3)	BDBM50021954 (UNASYN | 3,3-Dimethyl-4,4,7-trioxo-4lambda*6*-thia...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	7.76E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Beta-lactamase (Acinetobacter genomosp. 3)	BDBM50021954 (UNASYN | 3,3-Dimethyl-4,4,7-trioxo-4lambda*6*-thia...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.12E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Beta-lactamase (Acinetobacter genomosp. 3)	BDBM50021954 (UNASYN | 3,3-Dimethyl-4,4,7-trioxo-4lambda*6*-thia...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.17E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Beta-lactamase (Aeromonas allosaccharophila)	BDBM50021954 (UNASYN | 3,3-Dimethyl-4,4,7-trioxo-4lambda*6*-thia...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	4.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Beta-lactamase (Enterobacter cloacae)	BDBM50021954 (UNASYN | 3,3-Dimethyl-4,4,7-trioxo-4lambda*6*-thia...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.11E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Beta-lactamase (Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 /...)	BDBM50021954 (UNASYN | 3,3-Dimethyl-4,4,7-trioxo-4lambda*6*-thia...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.70E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Beta-lactamase (Serratia fonticola)	BDBM50021954 (UNASYN | 3,3-Dimethyl-4,4,7-trioxo-4lambda*6*-thia...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.27E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Beta-lactamase TEM (Escherichia coli)	BDBM50021954 (UNASYN | 3,3-Dimethyl-4,4,7-trioxo-4lambda*6*-thia...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	7.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Class A beta-lactamase BCL-1 (Bacillus clausii)	BDBM50021954 (UNASYN | 3,3-Dimethyl-4,4,7-trioxo-4lambda*6*-thia...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	75	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Beta-lactamase (Proteus mirabilis)	BDBM50021954 (UNASYN | 3,3-Dimethyl-4,4,7-trioxo-4lambda*6*-thia...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	342	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Beta-lactamase (Enterobacter cloacae)	BDBM50021954 (UNASYN | 3,3-Dimethyl-4,4,7-trioxo-4lambda*6*-thia...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.42E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Beta-lactamase (Citrobacter freundii)	BDBM50021954 (UNASYN | 3,3-Dimethyl-4,4,7-trioxo-4lambda*6*-thia...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	857	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Beta-lactamase TEM (Escherichia coli)	BDBM50021954 (UNASYN | 3,3-Dimethyl-4,4,7-trioxo-4lambda*6*-thia...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	557	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Beta-lactamase SHV-1 (Pseudomonas aeruginosa (g-Proteobacteria))	BDBM50021954 (UNASYN | 3,3-Dimethyl-4,4,7-trioxo-4lambda*6*-thia...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.71E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Beta-lactamase (Staphylococcus aureus)	BDBM50021954 (UNASYN | 3,3-Dimethyl-4,4,7-trioxo-4lambda*6*-thia...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.42E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Metallo-beta-lactamase type 2 (Bacteroides fragilis)	BDBM50021954 (UNASYN | 3,3-Dimethyl-4,4,7-trioxo-4lambda*6*-thia...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.14E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Beta-lactamase OXA-1 (Escherichia coli)	BDBM50021954 (UNASYN | 3,3-Dimethyl-4,4,7-trioxo-4lambda*6*-thia...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.37E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Beta-lactamase (Klebsiella oxytoca)	BDBM50021954 (UNASYN | 3,3-Dimethyl-4,4,7-trioxo-4lambda*6*-thia...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.71E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Beta-lactamase BRO-1 (Moraxella catarrhalis)	BDBM50021954 (UNASYN | 3,3-Dimethyl-4,4,7-trioxo-4lambda*6*-thia...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	107	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Beta-lactamase (Pseudomonas aeruginosa)	BDBM50021954 (UNASYN | 3,3-Dimethyl-4,4,7-trioxo-4lambda*6*-thia...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Beta-lactamase (Escherichia coli (strain K12))	BDBM50021954 (UNASYN | 3,3-Dimethyl-4,4,7-trioxo-4lambda*6*-thia...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.55E+4	n/a	n/a	n/a	n/a	7.0	37
TBA									Citation and Details
					More data for this Ligand-Target Pair
Beta-lactamase SHV-1 (Escherichia coli)	BDBM50021954 (UNASYN | 3,3-Dimethyl-4,4,7-trioxo-4lambda*6*-thia...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.92E+3	n/a	n/a	n/a	n/a	7.0	37
TBA									Citation and Details
					More data for this Ligand-Target Pair
Beta-lactamase TEM (Escherichia coli)	BDBM50021954 (UNASYN | 3,3-Dimethyl-4,4,7-trioxo-4lambda*6*-thia...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.07E+3	n/a	n/a	n/a	n/a	7.0	37
TBA									Citation and Details
					More data for this Ligand-Target Pair
RNA demethylase ALKBH5 (Human)	BDBM50021954 (UNASYN | 3,3-Dimethyl-4,4,7-trioxo-4lambda*6*-thia...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Alpha-ketoglutarate-dependent dioxygenase FTO (Human)	BDBM50021954 (UNASYN | 3,3-Dimethyl-4,4,7-trioxo-4lambda*6*-thia...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>4.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Bile salt export pump (Human)	BDBM50021954 (UNASYN | 3,3-Dimethyl-4,4,7-trioxo-4lambda*6*-thia...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.33E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
ATP-binding cassette sub-family C member 2 (Human)	BDBM50021954 (UNASYN | 3,3-Dimethyl-4,4,7-trioxo-4lambda*6*-thia...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.33E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
ATP-binding cassette sub-family C member 3 (Human)	BDBM50021954 (UNASYN | 3,3-Dimethyl-4,4,7-trioxo-4lambda*6*-thia...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.33E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
ATP-binding cassette sub-family C member 4 (Human)	BDBM50021954 (UNASYN | 3,3-Dimethyl-4,4,7-trioxo-4lambda*6*-thia...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.33E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Beta-lactamase OXA-1 (Escherichia coli)	BDBM50021954 (UNASYN | 3,3-Dimethyl-4,4,7-trioxo-4lambda*6*-thia...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.20E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Beta-lactamase TEM (Escherichia coli)	BDBM50021954 (UNASYN | 3,3-Dimethyl-4,4,7-trioxo-4lambda*6*-thia...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Beta-lactamase TEM (Escherichia coli)	BDBM50021954 (UNASYN | 3,3-Dimethyl-4,4,7-trioxo-4lambda*6*-thia...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.20E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Beta-lactamase (Staphylococcus aureus)	BDBM50021954 (UNASYN | 3,3-Dimethyl-4,4,7-trioxo-4lambda*6*-thia...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	6.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Beta-lactamase (Escherichia coli)	BDBM50021954 (UNASYN | 3,3-Dimethyl-4,4,7-trioxo-4lambda*6*-thia...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.50E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Beta-lactamase (Pseudomonas aeruginosa)	BDBM50021954 (UNASYN | 3,3-Dimethyl-4,4,7-trioxo-4lambda*6*-thia...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Beta-lactamase (Escherichia coli (strain K12))	BDBM50021954 (UNASYN | 3,3-Dimethyl-4,4,7-trioxo-4lambda*6*-thia...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	6.59E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Beta-lactamase TEM (Escherichia coli)	BDBM50021954 (UNASYN | 3,3-Dimethyl-4,4,7-trioxo-4lambda*6*-thia...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Beta-lactamase TEM (Escherichia coli)	BDBM50021954 (UNASYN | 3,3-Dimethyl-4,4,7-trioxo-4lambda*6*-thia...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Beta-lactamase (Escherichia coli (strain K12))	BDBM50021954 (UNASYN | 3,3-Dimethyl-4,4,7-trioxo-4lambda*6*-thia...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	6.59E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Beta-lactamase (Escherichia coli (strain K12))	BDBM50021954 (UNASYN | 3,3-Dimethyl-4,4,7-trioxo-4lambda*6*-thia...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	6.60E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Beta-lactamase TEM (Escherichia coli)	BDBM50021954 (UNASYN | 3,3-Dimethyl-4,4,7-trioxo-4lambda*6*-thia...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Metallo-beta-lactamase type 2 (Bacteroides fragilis)	BDBM50021954 (UNASYN | 3,3-Dimethyl-4,4,7-trioxo-4lambda*6*-thia...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair