BDBM50022418 (1-Carboxymethyl-cyclopentyl)-acetic acid(TMG)::3,3-tetramethyleneglutaric acid::CHEMBL80679

SMILES OC(=O)CC1(CC(O)=O)CCCC1

InChI Key InChIKey=FWPVKDFOUXHOKQ-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50022418   

TargetAldo-keto reductase family 1 member B1 [K65Q](Bos taurus (Cattle))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50022418((1-Carboxymethyl-cyclopentyl)-acetic acid(TMG) | 3...)
Affinity DataIC50:  1.00E+3nMAssay Description:In vitro inhibitory activity towards partially purified calf lens aldose reductase; value ranges from 10E-6 - 10E-7More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1 [K65Q](Bos taurus (Cattle))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50022418((1-Carboxymethyl-cyclopentyl)-acetic acid(TMG) | 3...)
Affinity DataIC50:  1.00E+4nMAssay Description:In vitro inhibition of partially purified calf lens aldose reductase; value ranges from 10E-5 to 10E-6More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1(Rattus norvegicus)
Chungnam National University

Curated by ChEMBL
LigandPNGBDBM50022418((1-Carboxymethyl-cyclopentyl)-acetic acid(TMG) | 3...)
Affinity DataIC50:  3.18E+4nMAssay Description:Inhibition of Sprague-Dawley rat lens alodse reductase by spectrofluorimetryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1(Rattus norvegicus)
Chungnam National University

Curated by ChEMBL
LigandPNGBDBM50022418((1-Carboxymethyl-cyclopentyl)-acetic acid(TMG) | 3...)
Affinity DataIC50:  2.87E+4nMAssay Description:Inhibition of Sprague-Dawley rat lense aldose reductase using DL-glyceraldehyde as substrate by spectrofluorometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed