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BDBM50022562 CHEMBL3298792

SMILES: CC(C)(C)OC(=O)NN(Cc1ccccc1)C(=O)CI

InChI Key: InChIKey=DKYMRAKSIWFPNE-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50022562   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
RAC-alpha serine/threonine-protein kinase AKT1


(Homo sapiens (Human))
BDBM50022562
PNG
(CHEMBL3298792)
Show SMILES CC(C)(C)OC(=O)NN(Cc1ccccc1)C(=O)CI
Show InChI InChI=1S/C14H19IN2O3/c1-14(2,3)20-13(19)16-17(12(18)9-15)10-11-7-5-4-6-8-11/h4-8H,9-10H2,1-3H3,(H,16,19)
PDB

UniProtKB/SwissProt
UniProtKB/TrEMBL

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 1.61E+4n/an/an/an/an/an/a



Virginia Commonwealth University

Curated by ChEMBL


Assay Description
Inhibition of AKT1 (unknown origin) after 1 hr by Z'-LYTE kinase assay in presence of 75 uM ATP


ACS Med Chem Lett 5: 462-7 (2014)


Article DOI: 10.1021/ml500088x
BindingDB Entry DOI: 10.7270/Q2VT1TNG
More data for this
Ligand-Target Pair