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BDBM50022886 CHEMBL3298107

SMILES: Oc1c(I)cc(I)cc1C(=O)Nc1ccc2ccccc2c1

InChI Key: InChIKey=MJQBWIKDVPOWEQ-UHFFFAOYSA-N

Data: 1 IC50

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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50022886   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Chitinase


(Onchocerca volvulus)
BDBM50022886
PNG
(CHEMBL3298107)
Show SMILES Oc1c(I)cc(I)cc1C(=O)Nc1ccc2ccccc2c1
Show InChI InChI=1S/C17H11I2NO2/c18-12-8-14(16(21)15(19)9-12)17(22)20-13-6-5-10-3-1-2-4-11(10)7-13/h1-9,21H,(H,20,22)
UniProtKB/TrEMBL

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 940n/an/an/an/an/an/a



The Scripps Research Institute

Curated by ChEMBL


Assay Description
Inhibition of Onchocerca volvulus L3 larvae chitinase using 20 uM 4-methylumbelliferyl-N,N',N''-beta-chitotrioside as substrate after 10 mins by micr...


J Med Chem 57: 5792-9 (2014)


Article DOI: 10.1021/jm5006435
BindingDB Entry DOI: 10.7270/Q23B61Q3
More data for this
Ligand-Target Pair