BDBM50023328 3-Pyrrolidin-2-yl-pyridine::CHEMBL1132::Nornicotine::US10667515, Compound nornicotine

SMILES: C1CNC(C1)c1cccnc1

InChI Key: InChIKey=MYKUKUCHPMASKF-UHFFFAOYSA-N

Data: 5 KI  2 IC50  1 Kd  4 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 12 hits for monomerid = 50023328   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Resistance to inhibitors of cholinesterase protein 3 (Pig roundworm)	BDBM50023328 (Nornicotine | 3-Pyrrolidin-2-yl-pyridine | CHEMBL1...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	2.57E+4	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Acetylcholine receptor subunit alpha/beta/delta/gamma (Pacific electric ray)	BDBM50023328 (Nornicotine | 3-Pyrrolidin-2-yl-pyridine | CHEMBL1...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	100	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Acetylcholine receptor subunit alpha/beta/delta/gamma (Pacific electric ray)	BDBM50023328 (Nornicotine | 3-Pyrrolidin-2-yl-pyridine | CHEMBL1...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	300	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-3/beta-4 (Rat)	BDBM50023328 (Nornicotine | 3-Pyrrolidin-2-yl-pyridine | CHEMBL1...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	6.14E+5	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-4/beta-2 (Rat)	BDBM50023328 (Nornicotine | 3-Pyrrolidin-2-yl-pyridine | CHEMBL1...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	3.75E+5	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-7 (Rat)	BDBM50023328 (Nornicotine | 3-Pyrrolidin-2-yl-pyridine | CHEMBL1...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	1.74E+4	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-7 (Human)	BDBM50023328 (Nornicotine | 3-Pyrrolidin-2-yl-pyridine | CHEMBL1...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	1.06	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-4/beta-2 (Human)	BDBM50023328 (Nornicotine | 3-Pyrrolidin-2-yl-pyridine | CHEMBL1...) Show SMILES Show InChI	GoogleScholar	UniChem		29	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-4/beta-2 (Rat)	BDBM50023328 (Nornicotine | 3-Pyrrolidin-2-yl-pyridine | CHEMBL1...) Show SMILES Show InChI	GoogleScholar	UniChem		30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-4/beta-2 (Rat)	BDBM50023328 (Nornicotine | 3-Pyrrolidin-2-yl-pyridine | CHEMBL1...) Show SMILES Show InChI	GoogleScholar	UniChem		30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-7 (Human)	BDBM50023328 (Nornicotine | 3-Pyrrolidin-2-yl-pyridine | CHEMBL1...) Show SMILES Show InChI	GoogleScholar	UniChem		730	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-7 (Human)	BDBM50023328 (Nornicotine | 3-Pyrrolidin-2-yl-pyridine | CHEMBL1...) Show SMILES Show InChI	GoogleScholar	UniChem		1.38E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair