BindingDB logo
myBDB logout

BDBM50023341 CHEMBL3334566

SMILES: C(c1ccc2nccn2c1)n1nnc2ncc(nc12)N1CCOCC1

InChI Key: InChIKey=FOAJIFMQJFGRJZ-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50023341   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Hepatocyte growth factor receptor


(Homo sapiens (Human))
BDBM50023341
PNG
(CHEMBL3334566)
Show SMILES C(c1ccc2nccn2c1)n1nnc2ncc(nc12)N1CCOCC1
Show InChI InChI=1S/C16H16N8O/c1-2-13-17-3-4-23(13)10-12(1)11-24-16-15(20-21-24)18-9-14(19-16)22-5-7-25-8-6-22/h1-4,9-10H,5-8,11H2
PDB
MMDB

KEGG

UniProtKB/SwissProt
UniProtKB/TrEMBL

B.MOAD
DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 787n/an/an/an/an/an/a



Hutchison MediPharma Limited

Curated by ChEMBL


Assay Description
Inhibition of c-Met (unknown origin) using Poly E4Y substrate and ATP incubated for 45 mins by fluorescence polarization assay


J Med Chem 57: 7577-89 (2014)


Article DOI: 10.1021/jm500510f
BindingDB Entry DOI: 10.7270/Q2JD4ZCR
More data for this
Ligand-Target Pair