BDBM50023727 CHEMBL3330170
SMILES FC(F)(F)c1cc(NC2CC2)n2nc(NC(=O)c3cccnc3)nc2c1
InChI Key InChIKey=XUKGFHHTSUKORV-UHFFFAOYSA-N
Data 4 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 50023727
TargetMitogen-activated protein kinase kinase kinase 5(Homo sapiens (Human))
NAS of Ukraine
Curated by ChEMBL
NAS of Ukraine
Curated by ChEMBL
Affinity DataIC50: 93nMAssay Description:Inhibition of ASK1 (unknown origin)More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase kinase kinase 5(Homo sapiens (Human))
NAS of Ukraine
Curated by ChEMBL
NAS of Ukraine
Curated by ChEMBL
Affinity DataIC50: 90nMAssay Description:Inhibition of ASK1 (unknown origin)More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase kinase kinase 5(Homo sapiens (Human))
NAS of Ukraine
Curated by ChEMBL
NAS of Ukraine
Curated by ChEMBL
Affinity DataIC50: 13nMAssay Description:Inhibition of V5 tagged human ASK1 expressed in HEK-293T cells assessed as reduction in T838 autophosphorylation incubated for 1 hrMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase kinase kinase 5(Homo sapiens (Human))
NAS of Ukraine
Curated by ChEMBL
NAS of Ukraine
Curated by ChEMBL
Affinity DataIC50: 131nMAssay Description:Inhibition of human ASK1 using myelin basic protein substrate pre-incubated for 20 mins before [33P]-ATP addition and measured after 2 hrs by filter-...More data for this Ligand-Target Pair