BDBM50024203 3-(2-Amino-ethyl)-1H-indol-4-ol::3-(2-Amino-ethyl)-1H-indol-4-ol(4-HT)::CHEMBL18855

SMILES NCCc1c[nH]c2cccc(O)c12

InChI Key InChIKey=FKIRTWDHOWAQGX-UHFFFAOYSA-N

Data  5 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50024203   

Target5-hydroxytryptamine receptor 2C(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50024203(3-(2-Amino-ethyl)-1H-indol-4-ol(4-HT) | 3-(2-Amino...)
Affinity DataKi:  40nMAssay Description:Evaluated for the binding affinity to porcine choroid plexus at 5-hydroxytryptamine 2C receptor binding site by using [3H]-MES as a radioligand.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Rat)
University of Lausanne

Curated by ChEMBL
LigandPNGBDBM50024203(3-(2-Amino-ethyl)-1H-indol-4-ol(4-HT) | 3-(2-Amino...)
Affinity DataKi:  95nMAssay Description:Binding affinity of a compound to rat brain 5-hydroxytryptamine 1A (serotonin) receptor assayed by radiolabeled [3H]-8-OH-DPAT ligand displacementMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2020
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Rat)
University of Lausanne

Curated by ChEMBL
LigandPNGBDBM50024203(3-(2-Amino-ethyl)-1H-indol-4-ol(4-HT) | 3-(2-Amino...)
Affinity DataKi:  95nMAssay Description:Evaluated for the binding affinity to hippocampus striatal membranes at 5-hydroxytryptamine 1A receptor binding site by using [3H]-8-OH- DPAT as a ra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2012
Entry Details Article
PubMed
TargetSerotonin 2 (5-HT2) receptor(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50024203(3-(2-Amino-ethyl)-1H-indol-4-ol(4-HT) | 3-(2-Amino...)
Affinity DataKi:  725nMAssay Description:Binding affinity to rat cortical membranes at 5-hydroxytryptamine 2 (5-HT2) receptor using [3H]KET as a radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1B(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50024203(3-(2-Amino-ethyl)-1H-indol-4-ol(4-HT) | 3-(2-Amino...)
Affinity DataKi:  1.05E+3nMAssay Description:Binding affinity (Ki) to rat cortical membranes at 5-HT1B binding site by using [125 I] ICYP as a radioligand.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2012
Entry Details Article
PubMed