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BDBM50024367 CHEMBL3330471

SMILES: [H][C@@]12COc3cc(ccc3N1C(=O)O[C@H]2CNC(=O)c1cc2c(Cl)cccc2s1)N1CCOCC1=O

InChI Key: InChIKey=VZBDNOAPUHGUFY-NJPLCYPENA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50024367   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Coagulation factor X


(Homo sapiens (Human))
BDBM50024367
PNG
(CHEMBL3330471)
Show SMILES Clc1cccc2sc(cc12)C(=O)NC[C@@H]1OC(=O)N2[C@H]1COc1cc(ccc21)N1CCOCC1=O
Show InChI InChI=1/C24H20ClN3O6S/c25-15-2-1-3-20-14(15)9-21(35-20)23(30)26-10-19-17-11-33-18-8-13(27-6-7-32-12-22(27)29)4-5-16(18)28(17)24(31)34-19/h1-5,8-9,17,19H,6-7,10-12H2,(H,26,30)/t17-,19-/s2
PDB
MMDB

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Similars

Article
PubMed
n/an/a>1.00E+5n/an/an/an/an/an/a



Chinese Academy of Sciences

Curated by ChEMBL


Assay Description
Inhibition of human factor 10a using N-Z-D-Arg-Gly-Arg-pNA, S-2765 chromogenic substrate


J Med Chem 57: 7770-91 (2014)


Article DOI: 10.1021/jm501045e
BindingDB Entry DOI: 10.7270/Q228095Z
More data for this
Ligand-Target Pair