BDBM50024458 5-oxo-ETE::CHEMBL18028::ETE-5-Oxo
SMILES CCCCC\C=C/C\C=C/CC=CC=CC(=O)CCCC(O)=O
InChI Key InChIKey=MEASLHGILYBXFO-KAXMYATKSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 10 hits for monomerid = 50024458
TargetLeukotriene B4 receptor 1(Homo sapiens (Human))
Schering-Plough Research Institute
Curated by PDSP Ki Database
Schering-Plough Research Institute
Curated by PDSP Ki Database
TargetLeukotriene B4 receptor 2(Homo sapiens (Human))
Schering-Plough Research Institute
Curated by PDSP Ki Database
Schering-Plough Research Institute
Curated by PDSP Ki Database
TargetOxoeicosanoid receptor 1(Homo sapiens (Human))
Hospital Del Mar Medical Research Institute (Imim)
Curated by ChEMBL
Hospital Del Mar Medical Research Institute (Imim)
Curated by ChEMBL
Affinity DataEC50: 220nMAssay Description:Agonist activity at human PK-tagged OXER1 expressed in CHOK1 cells assessed as EA-tagged beta-arrestin recruitment by beta-galactosidase enzyme fragm...More data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid lipoxygenase ALOX12(Homo sapiens (Human))
University Of California
Curated by ChEMBL
University Of California
Curated by ChEMBL
Affinity DataIC50: 1.50E+4nMAssay Description:Inhibition of human platelet 12-lipoxygenase by UV-visible spectrophotometryMore data for this Ligand-Target Pair
TargetOxoeicosanoid receptor 1(Homo sapiens (Human))
Hospital Del Mar Medical Research Institute (Imim)
Curated by ChEMBL
Hospital Del Mar Medical Research Institute (Imim)
Curated by ChEMBL
Affinity DataIC50: 3nMAssay Description:Desensitization of 5-oxo-ETE receptor in indo-1-labeled human neutrophils assessed as inhibition of 5-oxo-ETE-induced calcium mobilizationMore data for this Ligand-Target Pair
TargetOxoeicosanoid receptor 1(Homo sapiens (Human))
Hospital Del Mar Medical Research Institute (Imim)
Curated by ChEMBL
Hospital Del Mar Medical Research Institute (Imim)
Curated by ChEMBL
Affinity DataEC50: 7nMAssay Description:Agonist activity at 5-oxo-ETE receptor in human neutrophils assessed as stimulation of ca2+ mobilizationMore data for this Ligand-Target Pair
Affinity DataIC50: 1.80E+4nMAssay Description:In vitro inhibitory activity against 5-lipoxygenase from rat basophilic leukemia cells.More data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid lipoxygenase ALOX15B(Homo sapiens (Human))
University Of California
Curated by ChEMBL
University Of California
Curated by ChEMBL
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human reticulocyte 15-lipoxygenase-2 by UV-visible spectrophotometryMore data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Oryctolagus cuniculus (rabbit))
University Of California
Curated by ChEMBL
University Of California
Curated by ChEMBL
Affinity DataIC50: >2.50E+4nMAssay Description:Inhibition of rabbit reticulocyte 15-LOX by UV-visible spectrophotometryMore data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Homo sapiens (Human))
University Of California
Curated by ChEMBL
University Of California
Curated by ChEMBL
Affinity DataIC50: >2.50E+4nMAssay Description:Inhibition of human reticulocyte 15-lipoxygenase-1 by UV-visible spectrophotometryMore data for this Ligand-Target Pair