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BDBM50024545 3-Ethyl-1-propyl-4,5-dihydro-3H-[3,4']bipyridinyl-2,6-dione::CHEMBL38877

SMILES: CCCN1C(=O)CCC(CC)(C1=O)c1ccncc1

InChI Key: InChIKey=FDOHSFHXHVBARL-UHFFFAOYNA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50024545   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Cytochrome P450 19A1


(Homo sapiens (Human))
BDBM50024545
PNG
(3-Ethyl-1-propyl-4,5-dihydro-3H-[3,4']bipyridinyl-...)
Show SMILES CCCN1C(=O)CCC(CC)(C1=O)c1ccncc1
Show InChI InChI=1/C15H20N2O2/c1-3-11-17-13(18)5-8-15(4-2,14(17)19)12-6-9-16-10-7-12/h6-7,9-10H,3-5,8,11H2,1-2H3
PDB
MMDB

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Similars

Article
PubMed
n/an/a 3.10E+4n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibitory activity against human placental cytochrome P450 19A1


J Med Chem 30: 1550-4 (1987)


Article DOI: 10.1021/jm00392a004
BindingDB Entry DOI: 10.7270/Q2GM869Q
More data for this
Ligand-Target Pair