BDBM50025160 CHEMBL3337894
SMILES COc1cccc(CNC(=O)c2nc3scc(COCc4ccc(cc4)C(O)=O)c3c(=O)[nH]2)c1
InChI Key InChIKey=CDQRIIUMNLMHRH-UHFFFAOYSA-N
Data 14 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 14 hits for monomerid = 50025160
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human recombinant MMP1 using fluorescence peptide Cy3-PLGLK(Cy5Q)AR-NH2 substrate by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 18nMAssay Description:Inhibition of human recombinant MMP2 using fluorescence peptide Cy3-PLGLK(Cy5Q)AR-NH2 substrate by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 600nMAssay Description:Inhibition of human recombinant MMP3 using fluorescence peptide Cy3-PLGLK(Cy5Q)AR-NH2 substrate by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human recombinant MMP7 using fluorescence peptide Cy3-PLGLK(Cy5Q)AR-NH2 substrate by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 780nMAssay Description:Inhibition of human recombinant MMP8 using fluorescence peptide Cy3-PLGLK(Cy5Q)AR-NH2 substrate by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human recombinant MMP9 using fluorescence peptide Cy3-PLGLK(Cy5Q)AR-NH2 substrate by fluorescence assayMore data for this Ligand-Target Pair
TargetStromelysin-2(Homo sapiens (Human))
Zhaw Zurich University Of Applied Sciences
Curated by ChEMBL
Zhaw Zurich University Of Applied Sciences
Curated by ChEMBL
Affinity DataIC50: 358nMAssay Description:Inhibition of C-terminal tagged human recombinant MMP13 catalytic domain expressed in Escherichia coli using (5-FAM/QX) FRET peptide as substrate by ...More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human recombinant MMP14 using fluorescence peptide Cy3-PLGLK(Cy5Q)AR-NH2 substrate by fluorescence assayMore data for this Ligand-Target Pair
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
Takeda Pharmaceutical
Curated by ChEMBL
Takeda Pharmaceutical
Curated by ChEMBL
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human recombinant TACE using Cy3-PLAQAV(Cy5QL-2,3-diaminopropionic acid)-RSSSR-NH2 substrate by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 0.00690nMAssay Description:Inhibition of human recombinant MMP13 catalytic domain using fluorescence peptide Cy3-PLGLK(Cy5Q)AR-NH2 substrate by fluorescence assayMore data for this Ligand-Target Pair
TargetStromelysin-2(Homo sapiens (Human))
Zhaw Zurich University Of Applied Sciences
Curated by ChEMBL
Zhaw Zurich University Of Applied Sciences
Curated by ChEMBL
Affinity DataIC50: 358nMAssay Description:Inhibition of MMP10 (unknown origin) assessed using (5-FAM/QX) FRET peptide as substrate by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 0.190nMAssay Description:Inhibition of C-terminal tagged human recombinant MMP13 catalytic domain expressed in Escherichia coli using (5-FAM/QX) FRET peptide as substrate by ...More data for this Ligand-Target Pair
Affinity DataIC50: 0.190nMAssay Description:Inhibition of C-terminal tagged human recombinant MMP13 catalytic domain expressed in Escherichia coli using (5-FAM/QX) FRET peptide as substrate by ...More data for this Ligand-Target Pair
TargetStromelysin-2(Homo sapiens (Human))
Zhaw Zurich University Of Applied Sciences
Curated by ChEMBL
Zhaw Zurich University Of Applied Sciences
Curated by ChEMBL
Affinity DataIC50: 160nMAssay Description:Inhibition of human recombinant MMP10 using fluorescence peptide Cy3-PLGLK(Cy5Q)AR-NH2 substrate by fluorescence assayMore data for this Ligand-Target Pair