BDBM50025428 10,13-Dimethyl-1,6,7,8,9,10,11,12,13,14,15,16-dodecahydro-2H-cyclopenta[a]phenanthrene-3,17-dione::2,15-dimethyltetracyclo[8.7.0.0^{2,7}.0^{11,15}]heptadec-6-ene-5,14-dione::CHEMBL274826

SMILES C[C@]12CCC(=O)C=C1CC[C@@H]3[C@@H]2CC[C@]4([C@H]3CCC4=O)C

InChI Key InChIKey=AEMFNILZOJDQLW-UHFFFAOYSA-N

Data  1 KI  1 IC50

PDB links: 28 PDB IDs match this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50025428   

TargetAromatase(Human)
Tohoku College of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50025428(10,13-Dimethyl-1,6,7,8,9,10,11,12,13,14,15,16-dode...)
Affinity DataKi:  20nMAssay Description:Binding affinity for aromatase cytochrome P45019A1 by analysis of Dixon plotMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetAromatase(Human)
Tohoku College of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50025428(10,13-Dimethyl-1,6,7,8,9,10,11,12,13,14,15,16-dode...)
Affinity DataIC50: 300nMAssay Description:In vitro competitive inhibitory activity was measured on Cytochrome P450 19A1 of human placental microsomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)