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BDBM50025717 5-(4-Amino-phenyl)-1,3-dimethyl-1,6-dihydro-pyrazolo[4,3-d]pyrimidin-7-one::CHEMBL367705

SMILES: Cc1nn(C)c2c1nc([nH]c2=O)-c1ccc(N)cc1

InChI Key: InChIKey=ADQCDAFPEZXGEW-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50025717   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Adenosine receptor A1


(Rattus norvegicus (rat))
BDBM50025717
PNG
(5-(4-Amino-phenyl)-1,3-dimethyl-1,6-dihydro-pyrazo...)
Show SMILES Cc1nn(C)c2c1nc([nH]c2=O)-c1ccc(N)cc1
Show InChI InChI=1S/C13H13N5O/c1-7-10-11(18(2)17-7)13(19)16-12(15-10)8-3-5-9(14)6-4-8/h3-6H,14H2,1-2H3,(H,15,16,19)
PDB

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PC sid
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Similars

Article
PubMed
n/an/a 380n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Binding affinity against adenosine A1 receptor in rat brain membrane preparations using N6-[3H]-cyclohexyladenosine as a radioligand


J Med Chem 30: 91-6 (1987)


Article DOI: 10.1021/jm00384a016
BindingDB Entry DOI: 10.7270/Q2Q23Z84
More data for this
Ligand-Target Pair