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BDBM50025764 5-Oxo-1-[3-(quinolin-2-ylmethoxy)-phenyl]-pyrrolidine-3-carboxylic acid methyl ester::CHEMBL131070

SMILES: COC(=O)C1CN(C(=O)C1)c1cccc(OCc2ccc3ccccc3n2)c1

InChI Key: InChIKey=VQGIRZMLBWFEEP-UHFFFAOYNA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50025764   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Arachidonate 5-lipoxygenase


(Rattus norvegicus)
BDBM50025764
PNG
(5-Oxo-1-[3-(quinolin-2-ylmethoxy)-phenyl]-pyrrolid...)
Show SMILES COC(=O)C1CN(C(=O)C1)c1cccc(OCc2ccc3ccccc3n2)c1
Show InChI InChI=1/C22H20N2O4/c1-27-22(26)16-11-21(25)24(13-16)18-6-4-7-19(12-18)28-14-17-10-9-15-5-2-3-8-20(15)23-17/h2-10,12,16H,11,13-14H2,1H3
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 1.91E+4n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Ability to inhibit Lipoxygenase in vitro was determined


J Med Chem 30: 400-5 (1987)


Article DOI: 10.1021/jm00385a024
BindingDB Entry DOI: 10.7270/Q2K936JS
More data for this
Ligand-Target Pair