BDBM50025802 1-(4-Fluoro-benzyl)-1,3-dihydro-imidazole-2-thione::CHEMBL67229

SMILES Fc1ccc(Cn2cc[nH]c2=S)cc1

InChI Key InChIKey=AWRNKBMEDXPMIN-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50025802   

TargetDopamine beta-hydroxylase(Bos taurus)
TBA

Curated by ChEMBL
LigandPNGBDBM50025802(1-(4-Fluoro-benzyl)-1,3-dihydro-imidazole-2-thione...)
Affinity DataIC50:  4.70E+4nMAssay Description:Inhibitory Concentration against bovine Dopamine beta hydroxylase (DBH); Range is between (40-56)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDopamine beta-hydroxylase(Homo sapiens (Human))
Molecular Simulations

Curated by ChEMBL
LigandPNGBDBM50025802(1-(4-Fluoro-benzyl)-1,3-dihydro-imidazole-2-thione...)
Affinity DataIC50:  4.68E+4nMAssay Description:Inhibition of dopamine beta hydroxylaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDopamine beta-hydroxylase(Homo sapiens (Human))
Molecular Simulations

Curated by ChEMBL
LigandPNGBDBM50025802(1-(4-Fluoro-benzyl)-1,3-dihydro-imidazole-2-thione...)
Affinity DataIC50:  4.68E+4nMAssay Description:Inhibition of dopamine beta-hydroxylase (DbetaH) enzymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDopamine beta-hydroxylase(Rattus norvegicus)
University Of Illinois

Curated by ChEMBL
LigandPNGBDBM50025802(1-(4-Fluoro-benzyl)-1,3-dihydro-imidazole-2-thione...)
Affinity DataIC50:  4.68E+4nMAssay Description:Inhibition of dopamine beta-hydroxylase (DbetaH) in hypertensive rats when administered orally (or) intraperitoneallyMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed