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BDBM50025915 CHEMBL16622::[2-Benzyl-3-(formyl-hydroxy-amino)-propionylamino]-acetic acid

SMILES: ON(CC(Cc1ccccc1)C(=O)NCC(O)=O)C=O

InChI Key: InChIKey=XWNIIJNUTOPWBP-UHFFFAOYSA-N

Data: 1 KI  2 IC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50025915   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Thermolysin


(Bacillus thermoproteolyticus)
BDBM50025915
PNG
(CHEMBL16622 | [2-Benzyl-3-(formyl-hydroxy-amino)-p...)
Show SMILES ON(CC(Cc1ccccc1)C(=O)NCC(O)=O)C=O
Show InChI InChI=1S/C13H16N2O5/c16-9-15(20)8-11(13(19)14-7-12(17)18)6-10-4-2-1-3-5-10/h1-5,9,11,20H,6-8H2,(H,14,19)(H,17,18)
PDB
MMDB

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CHEMBL
PC cid
PC sid
UniChem

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Similars

Article
PubMed
3.40E+4n/an/an/an/an/an/an/an/a



Pohang University of Science and Technology

Curated by ChEMBL


Assay Description
Inhibitory activity against thermolysin using 2-furylacryloyl-Gly-Leu-NH2 as substrate at pH 7.2


Bioorg Med Chem Lett 8: 323-6 (1999)


Article DOI: 10.1016/s0960-894x(98)00023-7
BindingDB Entry DOI: 10.7270/Q2WM1CJ0
More data for this
Ligand-Target Pair
Neutral Endopeptidase (NEP)


(Rattus norvegicus (Rat))
BDBM50025915
PNG
(CHEMBL16622 | [2-Benzyl-3-(formyl-hydroxy-amino)-p...)
Show SMILES ON(CC(Cc1ccccc1)C(=O)NCC(O)=O)C=O
Show InChI InChI=1S/C13H16N2O5/c16-9-15(20)8-11(13(19)14-7-12(17)18)6-10-4-2-1-3-5-10/h1-5,9,11,20H,6-8H2,(H,14,19)(H,17,18)
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
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CHEMBL
PC cid
PC sid
UniChem

Patents


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Article
PubMed
n/an/a 10n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
In vitro inhibition of enkephalinase purified from rat kidney.


J Med Chem 28: 1158-69 (1985)


Article DOI: 10.1021/jm00147a007
BindingDB Entry DOI: 10.7270/Q20C4WB5
More data for this
Ligand-Target Pair
Aminopeptidase N


(Sus scrofa (Pig))
BDBM50025915
PNG
(CHEMBL16622 | [2-Benzyl-3-(formyl-hydroxy-amino)-p...)
Show SMILES ON(CC(Cc1ccccc1)C(=O)NCC(O)=O)C=O
Show InChI InChI=1S/C13H16N2O5/c16-9-15(20)8-11(13(19)14-7-12(17)18)6-10-4-2-1-3-5-10/h1-5,9,11,20H,6-8H2,(H,14,19)(H,17,18)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/a 8.5n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibitory activity against rabbit kidney aminopeptidase using 10 nM of [3H]Leu-enkephalin as substrate


J Med Chem 28: 1158-69 (1985)


Article DOI: 10.1021/jm00147a007
BindingDB Entry DOI: 10.7270/Q20C4WB5
More data for this
Ligand-Target Pair