BDBM50026014 CHEMBL1081284

SMILES [H][C@]12CN(c3ccc(c(C)c3)-c3ccnc4c(c(nn34)-c3ccncc3)-c3ccc(F)c(O)c3)[C@]([H])(CN1C)C2

InChI Key InChIKey=FBURAFZZOWGKPS-GOTSBHOMSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50026014   

TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50026014(CHEMBL1081284)
Affinity DataIC50: <0.320nMAssay Description:Inhibition of human recombinant B-Raf expressed in Sf9 cells assessed as inhibition of Mek1 phosphorylationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed