BDBM50026685 CHEMBL3335373

SMILES CC(C)c1cccc(Nc2nc3cc(Oc4ccnc(NC(C)=O)c4)ccc3n2C)c1

InChI Key InChIKey=CGKCRNMLFZNYKA-UHFFFAOYSA-N

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50026685   

TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50026685(CHEMBL3335373)
Affinity DataEC50:  50nMAssay Description:Inhibition of BRAF (unknown origin)-mediated ERK phosphorylation by cell-based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50026685(CHEMBL3335373)
Affinity DataIC50: <0.400nMAssay Description:Inhibition of BRAF V600E mutant (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed