BDBM50026690 2-[2-(2-{2-[2-{2-[2-(2-Amino-3-phenyl-propionylamino)-3-carboxy-propionylamino]-4-methylsulfanyl-butyrylamino}-3-(1H-indol-3-yl)-propionylamino]-acetylamino}-4-methylsulfanyl-butyrylamino)-3-(4-sulfo-phenyl)-propionylamino]-succinic acid(gastrin)(Glu-Gly-Pro-Trp-Leu-Glu-Glu-Glu-Glu-Glu-Ala-Tyr-Gly-Trp-Met-Asp-Phe-NH2)::CHEMBL413654

SMILES CSCC[C@@H](NC(=O)[C@@H](Cc1c[nH]c2ccccc12)NC(=O)CNC(=O)[C@@H](Cc1ccc(O)cc1)NC(=O)[C@@H](C)NC(=O)[C@@H](CCC(O)=O)NC(=O)[C@@H](CCC(O)=O)NC(=O)[C@@H](CCC(O)=O)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@@H]1CCCN1C(=O)CNC(=O)[C@@H](N)CCC(O)=O)C(=O)N[C@H](CC(O)=O)C(=O)N[C@H](Cc1ccccc1)C(N)=O

InChI Key InChIKey=AOXOCDRNSPFDPE-UKEONUMOSA-N

Data  1 IC50  2 Kd  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50026690   

TargetCholecystokinin receptor type A(RAT)
TBA

Curated by ChEMBL
LigandPNGBDBM50026690(2-[2-(2-{2-[2-{2-[2-(2-Amino-3-phenyl-propionylami...)
Affinity DataIC50:  0.200nMAssay Description:Compound was tested for in vitro inhibition of the binding of [125I]-(Nle11)-HG-13 to Histamine H2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGastrin/cholecystokinin type B receptor(Homo sapiens (Human))
National Cancer Institute-Frederick

Curated by ChEMBL
LigandPNGBDBM50026690(2-[2-(2-{2-[2-{2-[2-(2-Amino-3-phenyl-propionylami...)
Affinity DataKd:  3.20nMAssay Description:Tested in vitro for gastrin binding to gastrin receptors from guinea pig gastric glandsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGastrin/cholecystokinin type B receptor(RAT)
National Cancer Institute-Frederick

Curated by ChEMBL
LigandPNGBDBM50026690(2-[2-(2-{2-[2-{2-[2-(2-Amino-3-phenyl-propionylami...)
Affinity DataKd:  1.40nMAssay Description:Tested in vitro by the gastrin binding assay for the competitive binding with iodinated gastrin for the gastrin receptors in AR42J cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGastrin/cholecystokinin type B receptor(RAT)
National Cancer Institute-Frederick

Curated by ChEMBL
LigandPNGBDBM50026690(2-[2-(2-{2-[2-{2-[2-(2-Amino-3-phenyl-propionylami...)
Affinity DataEC50:  1.00E+3nMAssay Description:Tested for the 50% inhibition level against [125I]- gastrin binding in AR42J cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed