BDBM50026727 CHEMBL3331469

SMILES Cl.C(N(C1CNC1)c1ccccc1)c1ccc2ccccc2c1

InChI Key InChIKey=YYZODXXLBSUZSX-UHFFFAOYSA-N

Data  8 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50026727   

TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Korea University

Curated by ChEMBL
LigandPNGBDBM50026727(CHEMBL3331469)
Affinity DataIC50:  333nMAssay Description:Inhibition of human NET expressed in HEK293 cells at incubated for 15 mins by neurotransmitter reuptake assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Korea University

Curated by ChEMBL
LigandPNGBDBM50026727(CHEMBL3331469)
Affinity DataIC50:  678nMAssay Description:Inhibition of human DAT expressed in HEK293 cells at incubated for 15 mins by neurotransmitter reuptake assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 1A2(Homo sapiens (Human))
Korea University

Curated by ChEMBL
LigandPNGBDBM50026727(CHEMBL3331469)
Affinity DataIC50:  1.27E+4nMAssay Description:Inhibition of human recombinant CYP1A2 incubated for 5 mins by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Korea University

Curated by ChEMBL
LigandPNGBDBM50026727(CHEMBL3331469)
Affinity DataIC50:  12nMAssay Description:Inhibition of human SERT expressed in HEK293 cells at incubated for 15 mins by neurotransmitter reuptake assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C9(Homo sapiens (Human))
Korea University

Curated by ChEMBL
LigandPNGBDBM50026727(CHEMBL3331469)
Affinity DataIC50:  3.13E+3nMAssay Description:Inhibition of human recombinant CYP2C9 incubated for 5 mins by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Korea University

Curated by ChEMBL
LigandPNGBDBM50026727(CHEMBL3331469)
Affinity DataIC50:  1.33E+3nMAssay Description:Inhibition of human recombinant CYP3A4 incubated for 5 mins by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C19(Homo sapiens (Human))
Korea University

Curated by ChEMBL
LigandPNGBDBM50026727(CHEMBL3331469)
Affinity DataIC50:  270nMAssay Description:Inhibition of human recombinant CYP2C19 incubated for 5 mins by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
Korea University

Curated by ChEMBL
LigandPNGBDBM50026727(CHEMBL3331469)
Affinity DataIC50:  10nMAssay Description:Inhibition of human recombinant CYP2D6 incubated for 5 mins by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed