BDBM50026868 2-(1H-indol-3-yl)-N,N-dimethylethanamine::2-(3-indolyl)ethyldimethylamine::3-(2-dimethylaminoethyl)indole::3-[2-(dimethylamino)ethyl]indole::CHEMBL12420::DMT::N,N-dimethyl-1H-indole-3-ethylamine::N,N-dimethyltryptamine::WO2023019367, Compound DMT

SMILES CN(C)CCc1c[nH]c2ccccc12

InChI Key InChIKey=DMULVCHRPCFFGV-UHFFFAOYSA-N

Data  10 KI  1 Kd  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 14 hits for monomerid = 50026868   

Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Purdue University

Curated by ChEMBL
LigandPNGBDBM50026868(2-(1H-indol-3-yl)-N,N-dimethylethanamine | 2-(3-in...)
Affinity DataKi:  33nMAssay Description:Compound was tested for the displacement of [125I]-DOI from cloned human 5-hydroxytryptamine 2C receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Rattus norvegicus (rat))
Stanford University

Curated by PDSP Ki Database
LigandPNGBDBM50026868(2-(1H-indol-3-yl)-N,N-dimethylethanamine | 2-(3-in...)
Affinity DataKi:  42nMMore data for this Ligand-Target Pair
In DepthDetails PubMed
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Purdue University

Curated by ChEMBL
LigandPNGBDBM50026868(2-(1H-indol-3-yl)-N,N-dimethylethanamine | 2-(3-in...)
Affinity DataKi:  65nMAssay Description:Compound was tested for the displacement of [125I]-DOI from clone human 5-hydroxytryptamine 2A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
University Of Washington

Curated by PDSP Ki Database
LigandPNGBDBM50026868(2-(1H-indol-3-yl)-N,N-dimethylethanamine | 2-(3-in...)
Affinity DataKi:  68nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2B(Homo sapiens (Human))
Purdue University

Curated by ChEMBL
LigandPNGBDBM50026868(2-(1H-indol-3-yl)-N,N-dimethylethanamine | 2-(3-in...)
Affinity DataKi:  101nMAssay Description:Compound was tested for the displacement of [3H]-5-HT from clone human 5-hydroxytryptamine 2B receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Purdue University

Curated by ChEMBL
LigandPNGBDBM50026868(2-(1H-indol-3-yl)-N,N-dimethylethanamine | 2-(3-in...)
Affinity DataKi:  259nMAssay Description:Compound was tested for the displacement of [3H]-8-OH- DPAT from rat brain 5-hydroxytryptamine 1A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50026868(2-(1H-indol-3-yl)-N,N-dimethylethanamine | 2-(3-in...)
Affinity DataKi:  410nMAssay Description:Displacement of [3H]8-OH-DPAT from 5HT1A receptor by vacuum filtrationMore data for this Ligand-Target Pair
In DepthDetails Article
Target5-hydroxytryptamine receptor 2B(BOVINE)
Stanford University

Curated by PDSP Ki Database
LigandPNGBDBM50026868(2-(1H-indol-3-yl)-N,N-dimethylethanamine | 2-(3-in...)
Affinity DataKi:  550nMMore data for this Ligand-Target Pair
In DepthDetails PubMed
Target5-hydroxytryptamine receptor 2A(Rattus norvegicus (rat))
Stanford University

Curated by PDSP Ki Database
LigandPNGBDBM50026868(2-(1H-indol-3-yl)-N,N-dimethylethanamine | 2-(3-in...)
Affinity DataKi:  1.64E+3nMAssay Description:Displacement of [3H]MDL100907 from 5HT2A receptor in Sprague-Dawley rat brain by liquid scintillation spectroscopyMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Cavia porcellus (Guinea pig))
Institut F£R Pharmazeutische Und Medizinische Chemie Der Universit£T M£Nster

Curated by ChEMBL
LigandPNGBDBM50026868(2-(1H-indol-3-yl)-N,N-dimethylethanamine | 2-(3-in...)
Affinity DataKi:  1.50E+4nMAssay Description:Displacement of [3H](+)-pentazocine from sigma 1 receptor in guinea pig brain by scintillation analyzerMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2B(RAT)
TBA

Curated by ChEMBL
LigandPNGBDBM50026868(2-(1H-indol-3-yl)-N,N-dimethylethanamine | 2-(3-in...)
Affinity DataKd:  1.00E+3nMAssay Description:The binding affinity to 5-hydroxytryptamine 2B receptor of rat fundusMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Purdue University

Curated by ChEMBL
LigandPNGBDBM50026868(2-(1H-indol-3-yl)-N,N-dimethylethanamine | 2-(3-in...)
Affinity DataEC50:  22nMAssay Description:Agonist activity at 5HT2A receptor (unknown origin) expressed in HEK293 cells by FLIPR calcium flux assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Purdue University

Curated by ChEMBL
LigandPNGBDBM50026868(2-(1H-indol-3-yl)-N,N-dimethylethanamine | 2-(3-in...)
Affinity DataEC50:  22nMAssay Description:Agonist activity at 5-HT2A receptor (unknown origin) by calcium flux assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Purdue University

Curated by ChEMBL
LigandPNGBDBM50026868(2-(1H-indol-3-yl)-N,N-dimethylethanamine | 2-(3-in...)
Affinity DataEC50: <1.00E+4nMAssay Description:The dye is diluted with assay buffer (20mM HEPES in 1x HBSS, PH7.4); Probenecid was added to the final concentration of 5 mM; Hi. Vortexed vigorously...More data for this Ligand-Target Pair
In DepthDetails PubMed