BindingDB logo
myBDB logout

BDBM50027194 1-(4-Cyano-4,4-diphenyl-butyl)-piperidine-4-carboxylic acid ethyl ester::CHEMBL198308

SMILES: CCOC(=O)C1CCN(CCCC(C#N)(c2ccccc2)c2ccccc2)CC1

InChI Key: InChIKey=PFAYWWJBJWEALF-UHFFFAOYSA-N

Data: 1 IC50  1 EC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50027194   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Human herpesvirus 5 chemokine receptor


(Human cytomegalovirus (strain AD169) (HHV-5) (Huma...)
BDBM50027194
PNG
(1-(4-Cyano-4,4-diphenyl-butyl)-piperidine-4-carbox...)
Show SMILES CCOC(=O)C1CCN(CCCC(C#N)(c2ccccc2)c2ccccc2)CC1
Show InChI InChI=1S/C25H30N2O2/c1-2-29-24(28)21-14-18-27(19-15-21)17-9-16-25(20-26,22-10-5-3-6-11-22)23-12-7-4-8-13-23/h3-8,10-13,21H,2,9,14-19H2,1H3
PDB

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/an/a>1.00E+5n/an/an/an/a



Vrije Universiteit

Curated by PDSP Ki Database


Assay Description
Effective concentration against US28-mediated inositol phosphate production in COS-7 cells


J Med Chem 48: 6461-71 (2005)


Article DOI: 10.1021/jm050418d
BindingDB Entry DOI: 10.7270/Q2ZP4640
More data for this
Ligand-Target Pair
Human herpesvirus 5 chemokine receptor


(Human cytomegalovirus (strain AD169) (HHV-5) (Huma...)
BDBM50027194
PNG
(1-(4-Cyano-4,4-diphenyl-butyl)-piperidine-4-carbox...)
Show SMILES CCOC(=O)C1CCN(CCCC(C#N)(c2ccccc2)c2ccccc2)CC1
Show InChI InChI=1S/C25H30N2O2/c1-2-29-24(28)21-14-18-27(19-15-21)17-9-16-25(20-26,22-10-5-3-6-11-22)23-12-7-4-8-13-23/h3-8,10-13,21H,2,9,14-19H2,1H3
PDB

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 3.47E+4n/an/an/an/an/an/a



Vrije Universiteit

Curated by PDSP Ki Database


Assay Description
Inhibitory concentration against chemokine receptor US28 expressed in COS-7 cells using [125I]-CCL5


J Med Chem 48: 6461-71 (2005)


Article DOI: 10.1021/jm050418d
BindingDB Entry DOI: 10.7270/Q2ZP4640
More data for this
Ligand-Target Pair