BDBM50027256 Sarizotan

SMILES Fc1ccc(cc1)-c1cncc(CNC[C@H]2CCc3ccccc3O2)c1

InChI Key InChIKey=HKFMQJUJWSFOLY-OAQYLSRUSA-N

Data  3 KI  5 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50027256   

Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Pierre Fabre Research Center

Curated by ChEMBL
LigandPNGBDBM50027256(Sarizotan)
Affinity DataKi:  2.20nMAssay Description:Displacement of [3H]OH-DPAT from rat cortex 5HT1A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Pierre Fabre Research Center

Curated by ChEMBL
LigandPNGBDBM50027256(Sarizotan)
Affinity DataKi:  19nMAssay Description:Displacement of [3H]YM-09151-2 from rat striatum D2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Rattus norvegicus (rat))
Pierre Fabre Research Center

Curated by ChEMBL
LigandPNGBDBM50027256(Sarizotan)
Affinity DataKi:  2.14E+3nMAssay Description:Displacement of [3H]ketanserin from rat cortex 5HT2A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
University Of Bologna

Curated by ChEMBL
LigandPNGBDBM50027256(Sarizotan)
Affinity DataIC50: <6nMAssay Description:Binding affinity to human 5HT1A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
University Of Bologna

Curated by ChEMBL
LigandPNGBDBM50027256(Sarizotan)
Affinity DataEC50:  78nMAssay Description:Agonist activity at human 5HT1A receptor in HeLa cells assessed as stimulation of [35S]GTP-gamma-S bindingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 3A(Homo sapiens (Human))
University Of Bologna

Curated by ChEMBL
LigandPNGBDBM50027256(Sarizotan)
Affinity DataIC50: <6nMAssay Description:Binding affinity to 5HT3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(3) dopamine receptor(Homo sapiens (Human))
University Of Bologna

Curated by ChEMBL
LigandPNGBDBM50027256(Sarizotan)
Affinity DataIC50: <6nMAssay Description:Binding affinity to human dopaminergic D3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
University Of Bologna

Curated by ChEMBL
LigandPNGBDBM50027256(Sarizotan)
Affinity DataIC50: <6nMAssay Description:Binding affinity to human dopaminergic D2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(4) dopamine receptor(Homo sapiens (Human))
University Of Bologna

Curated by ChEMBL
LigandPNGBDBM50027256(Sarizotan)
Affinity DataIC50: <6nMAssay Description:Binding affinity to human dopaminergic D4 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed