BindingDB logo
myBDB logout

BDBM50027522 2-(2-Carboxy-3-phenyl-propionylamino)-4-methyl-pentanoic acid

SMILES: CC(C)CC(NC(=O)C(Cc1ccccc1)C([O-])=O)C([O-])=O

InChI Key: InChIKey=REOCNKZXONOGGX-UHFFFAOYSA-L

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50027522   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Neprilysin


(Mus musculus)
BDBM50027522
PNG
(2-(2-Carboxy-3-phenyl-propionylamino)-4-methyl-pen...)
Show SMILES CC(C)CC(NC(=O)C(Cc1ccccc1)C([O-])=O)C([O-])=O
Show InChI InChI=1S/C16H21NO5/c1-10(2)8-13(16(21)22)17-14(18)12(15(19)20)9-11-6-4-3-5-7-11/h3-7,10,12-13H,8-9H2,1-2H3,(H,17,18)(H,19,20)(H,21,22)/p-2
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
CHEBI
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 700n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
50% Inhibitory potency against enkephalinase from mouse striatum.


J Med Chem 26: 60-5 (1983)


Article DOI: 10.1021/jm00355a013
BindingDB Entry DOI: 10.7270/Q2Q81DP6
More data for this
Ligand-Target Pair
Angiotensin-converting enzyme


(Mus musculus)
BDBM50027522
PNG
(2-(2-Carboxy-3-phenyl-propionylamino)-4-methyl-pen...)
Show SMILES CC(C)CC(NC(=O)C(Cc1ccccc1)C([O-])=O)C([O-])=O
Show InChI InChI=1S/C16H21NO5/c1-10(2)8-13(16(21)22)17-14(18)12(15(19)20)9-11-6-4-3-5-7-11/h3-7,10,12-13H,8-9H2,1-2H3,(H,17,18)(H,19,20)(H,21,22)/p-2
Reactome pathway
KEGG

UniProtKB/SwissProt
UniProtKB/TrEMBL

B.MOAD
GoogleScholar
CHEBI
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a>1.00E+6n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
50% Inhibitory potency against Angiotensin I converting enzyme from mouse striatum.


J Med Chem 26: 60-5 (1983)


Article DOI: 10.1021/jm00355a013
BindingDB Entry DOI: 10.7270/Q2Q81DP6
More data for this
Ligand-Target Pair