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BDBM50027993 CHEMBL290573::cis -Dimethyl-(3-phenyl-3-pyridin-3-yl-allyl)-amine;1.5C2H4O4

SMILES: CN(C)C\C=C(\c1ccccc1)c1cccnc1

InChI Key: InChIKey=JQUWEEDFHZIBHG-YBEGLDIGSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50027993   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Norepinephrine Monoamine transporters


(Rattus norvegicus)
BDBM50027993
PNG
(CHEMBL290573 | cis -Dimethyl-(3-phenyl-3-pyridin-3...)
Show SMILES CN(C)C\C=C(\c1ccccc1)c1cccnc1
Show InChI InChI=1S/C16H18N2/c1-18(2)12-10-16(14-7-4-3-5-8-14)15-9-6-11-17-13-15/h3-11,13H,12H2,1-2H3/b16-10-
Reactome pathway
KEGG

UniProtKB/TrEMBL

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 2.70E+4n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
In vitro inhibition of accumulation of (-)-[3H]-Norepinephrine (NA) in mouse brain slices


J Med Chem 24: 1499-507 (1982)


Article DOI: 10.1021/jm00144a025
BindingDB Entry DOI: 10.7270/Q2BG2N05
More data for this
Ligand-Target Pair
Monoamine transporters; Norepinephrine & serotonin


(Rattus norvegicus (rat))
BDBM50027993
PNG
(CHEMBL290573 | cis -Dimethyl-(3-phenyl-3-pyridin-3...)
Show SMILES CN(C)C\C=C(\c1ccccc1)c1cccnc1
Show InChI InChI=1S/C16H18N2/c1-18(2)12-10-16(14-7-4-3-5-8-14)15-9-6-11-17-13-15/h3-11,13H,12H2,1-2H3/b16-10-
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 3.70E+3n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
In vitro inhibition of accumulation of [14C]-5-HT (5-HT) in mouse brain slices


J Med Chem 24: 1499-507 (1982)


Article DOI: 10.1021/jm00144a025
BindingDB Entry DOI: 10.7270/Q2BG2N05
More data for this
Ligand-Target Pair