BDBM50028888 (3S,4R)-1-(4-Methoxy-phenyl)-3,4-diphenyl-3-(3-phenyl-propyl)-azetidin-2-one::CHEMBL49683

SMILES COc1ccc(cc1)N1[C@H](c2ccccc2)[C@@](CCCc2ccccc2)(C1=O)c1ccccc1

InChI Key InChIKey=VEQHEOQNNHYICV-VEEOACQBSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50028888   

TargetSterol O-acyltransferase 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50028888((3S,4R)-1-(4-Methoxy-phenyl)-3,4-diphenyl-3-(3-phe...)
Affinity DataIC50:  6.00E+3nMAssay Description:Inhibition of Acyl coenzyme A:cholesterol acyltransferase (ACAT)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSterol O-acyltransferase 1(Rattus norvegicus)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50028888((3S,4R)-1-(4-Methoxy-phenyl)-3,4-diphenyl-3-(3-phe...)
Affinity DataIC50:  6.00E+3nMAssay Description:Concentration required for 50% inhibition of Acyl coenzyme A:cholesterol acyltransferase activity using microsomal ACAT assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed